文献类型：期刊文献

中文题名：正电子发射型计算机断层显像技术在针刺研究中的应用进展

英文题名：Progress of application of PET-CT technology in acupuncture research

作者：李丽[1];严兴科[1];马翠[1];魏玉婷[1];窦婷婷[1]

第一作者：李丽

机构：[1]甘肃中医药大学针灸推拿学院,兰州730000

第一机构：甘肃中医药大学针灸推拿学院

年份：2025

卷号：50

期号：10

起止页码：1211

中文期刊名：针刺研究

外文期刊名：Acupuncture Research

收录：;北大核心:【北大核心2023】；

基金：2023年甘肃省省级重点人才项目(No.甘组通字〔2023〕20号);2023年度甘肃省联合科研基金一般项目(No.23JRRA1522);2024年高校教师创新基金项目(No.2024A-082);甘肃省自然科学基金B类项目(No.21JR1RA266)。

语种：中文

中文关键词：正电子发射型计算机断层显像技术;针刺;机制;综述

外文关键词：PET-CT;Acupuncture;Mechanism;Review

摘要：正电子发射型计算机断层显像技术(PET-CT)融合了功能代谢显像和解剖结构显像,代表着当前核医学影像技术的最高水平,在针刺效应机制的研究中应用愈加广泛。本文梳理了PET-CT技术在针刺临床及实验中的应用概况,PET-CT技术可以从脑功能活动和结构层面证实针灸的作用效应,包括穴位效应特异性、腧穴配伍效应、针刺得气效应、针刺双向调节效应等的脑功能机制。当前PET-CT技术主要用于脑系病症的针刺中枢机制探索研究,其次在脾胃系病症、心系病症和妇科病症中也较为常用。PET-CT技术为针刺研究提供了直观可视化的检测手段和更直接、精准的数据依据,能够体现针刺多靶点、多途径、多层次的整体调节特点和优势,为针刺效应机制的深入研究提供了有效手段和技术支撑。
Positron emission computed tomography(PET-CT),which combines functional metabolism imaging and anatomical structure imaging,represents the highest level of nuclear medicine imaging technology,and is increasingly used in the study of acupuncture effect mechanism.In the present paper,we review the recent progress of application of PET-CT technology in acupuncture clinic and experimental study,and conclude that the advantages of PET-CT technology are that it can confirmthe acupuncture effect fromthe level of brain functional activities and structure,including the brain functional mechanismof acupoint effect specificity,acupoint compatibility effect,acupuncture Deqi effect,and bidirectional regulation effect of acupuncture,etc.At present,PET-CT technology is mainly used to explore the central mechanismof acupuncture in improving brain diseases,and is also commonly used in gastrointestinal diseases,cardiovascular diseases and gynecological diseases.PET-CT technology provides intuitive and visual detection means and a more direct and accurate data basis for acupuncture research,which can reflect the overall regulation characteristics and advantages of acupuncture with multi-targets,multi-pathways and multi-levels,and provides effective means and technical support for the in-depth study on the underlying mechanisms of acupuncture effects.