文献类型：期刊文献

英文题名：Differential diagnostic value of magnetic resonance diffusion-weighted imaging and apparent diffusion coefficient for renal clear cell carcinoma and non-clear cell carcinoma

作者：Li, Xiaozhong[1,3];Xiang, Xuyang[2];Lin, Hui Ting[2]

第一作者：李孝忠

通信作者：Li, XZ[1]

机构：[1]Gansu Univ Chinese Med, Dept Radiol, Affiliated Hosp, Lanzhou 730020, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Clin Med Sch 1, Lanzhou 730000, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Dept Radiol, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730020, Gansu, Peoples R China

第一机构：甘肃中医药大学第二附属医院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Dept Radiol, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730020, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2023

卷号：25

期号：2

外文期刊名：ONCOLOGY LETTERS

收录：;Scopus(收录号：2-s2.0-85146073727);WOS:【SCI-EXPANDED(收录号:WOS:000909537600001)】；

语种：英文

外文关键词：non-clear cell renal cell carcinoma; MRI; clear cell renal cell carcinoma; diffusion-weighted imaging; apparent diffusion coefficient; differential diagnosis

摘要：Accurate identification of renal cell carcinoma (RCC) subtypes before surgery is important to determine appropriate surgical methods and clinical prognosis. The objective of the present study was to investigate the differential diagnostic value of magnetic resonance diffusion-weighted imaging (MRI-DWI) and the measured apparent diffusion coefficient (ADC) in clear cell (cc) RCC and non-ccRCC. Imaging data (DWI and ADC) from 100 patients with pathologically confirmed RCC from March 2018 to March 2021 in Affiliated Hospital of Gansu University of Chinese Medicine, (Lanzhou, China) were retrospectively analyzed, including 32 cases of non-ccRCC (21 cases of chromophobe and 11 cases of papillary cell carcinoma) and 68 cases of ccRCC. Patients underwent MRI examination, including high and low B-value DWI, to compare the imaging features of the two RCC subtypes and the ADC values of tumor sites were measured. The results of the DWI and ADC were statistically different between the two RCC subtypes (P<0.01). The DWI of ccRCC was primarily low, equal or slightly high signal. ADC of ccRCC was mainly equal or slightly high signal and the high B-value DWI signal was lower than the low B-value DWI. DWI of non-ccRCC was mostly obviously high signal. ADC of non-ccRCC was mostly uniform, obviously low signal and the high B-value DWI signal was markedly higher than the low B-value DWI. The ADC values of non-ccRCC were lower than those of ccRCC, and the ADC values <1.42 +/- 0.48x10(-3) mm(2)/s were mostly non-ccRCC. In conclusion, MRI-DWI and ADC can be used to differentiate subtypes of RCC to determine appropriate surgical methods and clinical prognosis.