文献类型：期刊文献

中文题名：舒经玫瑰胶囊对小鼠原发性痛经血浆血栓素B_2、6-酮-前列腺素F_(1α)的影响

英文题名：Effect of Red Rose Capsule for Releasing the Dysmenorrhea on Plasma Thromboxane B_2 and 6-Keto-Prostaglandin F_(1α) of Primary Dysmenorrhea Mice

作者：王昕[1];姚凝[1];刘健鸿[1];裴培田[1]

第一作者：王昕

机构：[1]甘肃中医学院

第一机构：甘肃中医药大学

年份：2008

卷号：15

期号：6

起止页码：41

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2011_2012】；

基金：甘肃省教育厅资助(017Q-05)

语种：中文

中文关键词：舒经玫瑰胶囊;原发性痛经:血栓素B2,6-酮-前列腺素F1α;小鼠

外文关键词：Red Rose Capsule for Releasing the Dysmenorrhea; primary dysmenorrheal; TXB2; 6-Keto-PGF1α; mice

摘要：目的探讨舒经玫瑰胶囊对小鼠原发性痛经的保护作用。方法取体重24～26 g未孕健康小鼠64只,随机分4组:生理盐水组、舒经玫瑰胶囊小剂量组(0.8 g/25 g)、舒经玫瑰胶囊大剂量组(8 g/25 g)、月月舒对照组(50 mg/25 g),以小鼠血浆中血栓素B2(TXB2)、6-酮-前列腺素F1α(6-Keto-PGF1α)为指标进行实验观察。结果舒经玫瑰胶囊对原发性痛经小鼠血浆中的6-Keto-PGF1α升高与TXB2的降低有显著作用(P<0.01)。结论舒经玫瑰胶囊通过对TXB2及6-Keto-PGF1α含量的影响,对原发性痛经有保护作用。
Objective To approach the protective actions of Red Rose Capsule for Releasing the Dysmenorrhea （RRC） on the mice of primary dysmenorrhea. Method Sixty four health rats with the similar menstrual cycle were divided into four groups - NS group, RRC low dose group, RRC high dose group and Yueyueshu group. The indexes of TXB2 and 6-Keto-PGF1α in plasma were observed. Result RRC had significant effect on increasing 6-Keto-PGF1α and decreasing TXB2 in plasma of primary dysmenorrhea mice. Conclusion RRC has protective action against primary dysmenorrhea by influencing the content of TXB2 and 6-Keto-PGF1α.