文献类型：期刊文献

英文题名：Insecticidal and acetylcholine esterase inhibition activity of Rhododendron thymifolium essential oil and its main constituent against two stored product insects

作者：Liang, Jun-yu[1];Yang, Ying-ying[1];An, Yue[1];Shao, Ya-zhou[1];He, Chun-yu[2];Zhang, Ji[1,3];Jia, Ling-yun[1]

第一作者：Liang, Jun-yu

通信作者：Jia, LY[1]

机构：[1]Northwest Normal Univ, Coll Life Sci, Lanzhou 730070, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Coll Pharm, Lanzhou, Gansu, Peoples R China;[3]Northwest Normal Univ, Northwest Univ, New Rural Dev Res Inst, Lanzhou, Gansu, Peoples R China

第一机构：Northwest Normal Univ, Coll Life Sci, Lanzhou 730070, Gansu, Peoples R China

通信机构：[1]corresponding author), Northwest Normal Univ, Coll Life Sci, Lanzhou 730070, Gansu, Peoples R China.

年份：2021

卷号：56

期号：4

起止页码：423

外文期刊名：JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES

收录：;EI(收录号：20211110069377);Scopus(收录号：2-s2.0-85102208105);WOS:【SCI-EXPANDED(收录号:WOS:000626324700001)】；

基金：Gansu Higher Education Industry Support Program (2020C-9); Special Foundation Projects for Guiding Technological and Development of Gansu Province (No. 2019ZX-05).

语种：英文

外文关键词：Rhododendron thymifolium; essential oil; germacrone; bioactivities; Lasioderma serricorne; Tribolium castaneum; acetylcholinesterase

摘要：In this work, we investigated the bioactivities of the essential oil (EO) extracted from the Rhododendron thymifolium and its principal germacrone against Lasioderma serricorne and Tribolium castaneum. The EO was obtained by steam distillation. Germacrone was obtained by cryogenic crystallization. The bioactivity of EO and germacrone was tested via contact and repellent activity assays. The results showed that EO and germacrone possessed contact and repellent activities against two species of insects. EO exhibited obvious contact activity against the L. serricorn adults, larvae and T. castaneum larvae with LD50 values of 29.15 mu g/adult, 42.73 mu g/larva, 19.65 mu g/larva respectively. Germacrone exhibited excellent contact activity against the L. serricorne adults, larvae and the T. castaneum larvae with LD50 values of 17.18 mu g/adult, 20.94 mu g/larva, 20.93 mu g/larva respectively. And at the highest testing concentrations (78.63 and 15.73 nL/cm(2)), the repellent activity of EO and germacrone on two target insects was comparable to that of the positive control (DEET) after 30 h exposure. In especially, in the treatment of the 120 h after the repellent activity of EO and germacrone against T.castaneum adults and larvae were still very significant and showed the same level percentage repellency as DEET. Meanwhile, germacrone exhibited inhibition of acetylcholinesterase activity with IC50 values of 3%. The results indicated that the EO of R. thymifolium and germacrone had the potential to be developed as natural insecticides and repellents for the control of T. castaneum and L. serricorne.