文献类型：期刊文献

中文题名：兰州地区与甘南藏族地区IgA血管炎儿童人口学及临床特征分析

英文题名：The Demographic Characteristics and the Clinical Features of Children with IgA Vasculitis at Onsetin Lanzhou Area and Gannan Tibetan Area

作者：张帆[1];夏晓黎[1];李永荣[1];谢海彬[1];把得祥[2]

第一作者：张帆

机构：[1]甘肃中医药大学附属医院老年病科,甘肃兰州730020;[2]碌曲县人民医院内儿科,甘肃碌曲747200

第一机构：甘肃中医药大学第二附属医院

年份：2020

卷号：34

期号：10

起止页码：1139

中文期刊名：中国皮肤性病学杂志

外文期刊名：The Chinese Journal of Dermatovenereology

收录：CSTPCD;;北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

语种：中文

中文关键词：IgA血管炎;儿童;兰州地区;甘南藏族地区;临床特征

外文关键词：IgA vasculitis;Children;Lanzhou area;Gannan Tibetan area;Clinical characteristics

摘要：目的比较分析兰州地区与甘南藏族地区儿童IgA血管炎临床特点及人口学特征。方法收集2016年6月-2019年5月在甘肃中医药大学附属医院及碌曲县人民医院诊断为IgA血管炎,居住地为兰州地区和甘南藏族地区的共354例儿童患者资料。采用SPSS25.0统计软件回顾性分析两组IgA血管炎儿童人口学及临床特征。结果甘南藏族地区IgA血管炎儿童发病平均年龄高于兰州地区(P<0.05)。兰州地区发病季节主要在夏季,甘南藏族地区主要在春、夏两季(P<0.05)。兰州地区儿童发病早期(发病3 d内)就诊率(29.41%)低于甘南藏族地区(61.19%)。甘南藏族地区儿童65.67%为轻度紫癜,高于兰州地区(49.01%);兰州地区关节受累儿童为35.29%,低于甘南藏族地区(46.27%);甘南藏族地区儿童14.93%为复发就诊,高于兰州地区(3.92%),以上差异均有统计学意义(P均<0.05)。结论甘南藏族地区IgA血管炎儿童发病平均年龄高,发病季节为春、夏两季,而兰州地区为夏季为主。两地女童发病比例高于男童。甘南藏族地区儿童早期就诊率高,兰州地区儿童皮肤紫癜表现较重,甘南藏族地区儿童关节受累率较高。
Objective To compare and analyze the clinical features and demographic characteristics of children patients with IgA vasculitis from Lanzhou City and Gannan Tibetan Autonomous Prefecture.Methods From June 2016 to May 2019,354 cases of children were diagnosed as IgA vasculitis in the Affiliated Hospital of Gansu University of Traditional Chinese Medicine and Luqu County People's Hospital were collected.The demographic characteristics and clinical features in the two groups were retrospectively analyzed by SPSS25.0 statistical software.Results The average age of children with IgA vasculitis in Gannan Tibetan Autonomous Prefecture was higher than that in Lanzhou area(P<0.05).The onset season in Lanzhou area was in summer,while the Gannan Tibetan area was in spring and summer(P<0.05).The early consultation rate(29.41%)of children in Lanzhou area at the early stage of onset was lower than that in Gannan Tibetan Autonomous Prefecture(61.19%).Most children(65.67%)were diagnosed as mild purpura in Gannan Tibetan Autonomous Prefecture,which was higher than that in Lanzhou area(49.01%),and the difference was statistically significant(P<0.05).Few children(35.29%)with joint involvement in Lanzhou area and it was significantly lower than that in Gannan Tibetan Autonomous Prefecture(46.27%)(P<0.05).Children(14.93%)in Gannan Tibetan Autonomous Prefecture visited the clinic for relapse,was higher than that in Lanzhou area(3.92%).The difference was statistically significant(P<0.05).Conclusion Children with IgA vasculitis in Gannan Tibetan Autonomous Prefecture have onset of the disease at higher average age,in spring and summer,while children in Lanzhou area mainly in summer.The incidence of female children is higher in both areas.However,the consultation rate of children is higher in Gannan Tibetan Autonomous Prefecture at the early stage of onset.The skin purpura of children in Lanzhou area is more severe.The joint involvement rate of children in Gannan Tibetan Autonomous Prefecture is higher.