文献类型：期刊文献

中文题名：2018年甘肃省肿瘤登记地区胃癌流行特征及2010-2018年变化趋势

英文题名：Incidence and Mortality of Stomach Cancer in Cancer Registration Areas of Gansu Province in 2018 and Trend from 2010 to 2018

作者：朱奕潼[1];袁浩冉[2];丁高恒[3];乔友林[4]

第一作者：朱奕潼

机构：[1]纽约大学研究生文理学院心理系,美国纽约10003;[2]甘肃中医药大学公共卫生学院,甘肃兰州730000;[3]甘肃省肿瘤医院,甘肃兰州730050;[4]中国医学科学院北京协和医学院群医学及公共卫生学院,北京100730

第一机构：纽约大学研究生文理学院心理系,美国纽约10003

年份：2022

卷号：31

期号：12

起止页码：992

中文期刊名：中国肿瘤

外文期刊名：China Cancer

收录：CSTPCD;;北大核心:【北大核心2020】；CSCD:【CSCD2021_2022】；

语种：中文

中文关键词：胃癌;发病率;死亡率;趋势;甘肃

外文关键词：stomach cancer;incidence;mortality;trend;Gansu

摘要：[目的]分析2018年甘肃省肿瘤登记地区胃癌发病与死亡情况及2010—2018年胃癌趋势变化情况。[方法]按照国家癌症中心制定的数据质量审核评价标准,对甘肃省符合质量控制标准要求的15个肿瘤登记点上报的胃癌发病、死亡和人口数据进行汇总分析。按性别、城乡和年龄组分层计算发病(死亡)率、标化发病(死亡)率、0~74岁累积率等统计指标。中标率和世标率分别采用2000年全国普查标准人口年龄构成和Segi’s世界标准人口年龄构成计算。利用Joinpoint线性回归模型分析计算2010—2018年甘肃省胃癌发病率和死亡率的年度变化百分比(APC)。[结果] 2018年甘肃省肿瘤登记地区胃癌发病率为58.31/10万,中标率为42.60/10万,世标率为47.11/10万,累积率(0~74岁)为5.61%,占全部恶性肿瘤发病的23.05%,居发病顺位第1位。胃癌死亡率为37.15/10万,中标率为26.90/10万,世标率为30.42/10万,累积率(0~74岁)为3.43%,占全部恶性肿瘤死亡的26.37%,居死亡顺位第1位。发病率和死亡率分别在40岁和45岁开始随年龄增长呈上升趋势,高峰分别在70~74岁和80~84岁年龄组。2010—2018年甘肃省肿瘤登记地区胃癌中标发病率呈下降趋势(APC=-3.01%,95%CI:-5.87%~-0.07%),差异有统计学意义(P<0.05);胃癌中标死亡率从2010年的49.41/10万下降至2018年的33.43/10万(APC=-2.34%,95%CI:-5.98%~1.45%),差异无统计学意义(P>0.05)。在地区分布中,临潭县中标发病率和中标死亡率均为最高,白银市白银区中标发病率与中标死亡率均为最低。[结论] 2010—2018年甘肃省肿瘤登记地区胃癌中标发病率虽呈下降趋势,但其发病率和死亡率仍处我国较高水平,应根据年龄和地区分布差异,加强开展健康宣传教育,提高胃癌相关知识知晓率,控制危险因素,加强高危人群的识别与评估,早发现、早诊断、早治疗,切实做好胃癌的早期防控工作。
[Purpose] To analyze the incidence and mortality of stomach cancer in the cancer registration areas of Gansu Province in 2018 and the trend from 2010 to 2018. [Methods] According to the data quality review and evaluation standards formulated by the National Cancer Center, the stomach cancer incidence, mortality and population data reported by 15 cancer registries in Gansu Province that met the quality control standards were analyzed. The incidence(mortality) rate,age-standardized incidence(mortality) rate and cumulative rate(0~74 years old) were calculated according to areas(urban and rural) and age groups. The age-standardized rate was calculated and adjusted by Chinese standard population in 2000(ASIRC, ASMRC) and world standard(Segi’s)population(ASIRW, ASMRW), respectively. Using the Joinpoint linear regression model to analyze and calculate the annual percentage change(APC) of the incidence and mortality of stomach cancer in Gansu Province from 2010 to 2018. [Results] In 2018, the crude incidence of stomach cancer in the cancer registration areas of Gansu Province was 58.31/105, ASIRC and ASIRW were 42.60/105and 47.11/105, respectively, and the cumulative rate(0~74 years old) was 5.61%, accounting for 23.05% of all cancer, ranking the first in the incidence. The crude mortality rate was 37.15/105, ASMRC and ASMRW were 26.90/105and 30.42/105, respectively, and the cumulative rate(0~74 years old) was 3.43%, accounting for 26.37% of all cancer, ranking the first in the order of mortality. Incidence and mortality began to increase with age at 40 and 45 years of age, respectively, and peaked in the 70~74 and 80~84 age groups, respectively. From 2010 to 2018, the ASIRC of stomach cancer in the cancer registration areas of Gansu Province showed a downward trend(APC=-3.01%, 95%CI:-5.87%~-0.07%), and the difference was statistically significant(P<0.05). The mortality rate of stomach cancer ASMRC from 49.41/105in 2010 to 33.43/105in 2018(APC=-2.34%, 95%CI:-5.98%~1.45%), and the difference was not statistically significant(P>0.05). In the regional distribution, Lintan County had the highest incidence rate and mortality rate. Baiyin District had the lowest incidence rate and mortality rate. [Conclusion] Although the incidence of stomach cancer in the cancer registration areas of Gansu Province showed a downward trend from 2010 to 2018, the incidence and mortality were still at a relatively high level. It is necessary to promote the awareness of stomach cancer-related knowledge, to control risk factors and strengthen the identification and evaluation of high-risk groups, and to carry out early detection,early diagnosis and early treatment for prevention and control of stomach cancer.