文献类型：期刊文献

中文题名：2009—2015年甘肃省肿瘤登记地区乳腺癌流行特征及变化趋势分析

英文题名：Epidemiological characteristics and trend analysis of breast cancer in cancer registration areas of Gansu province,2009—2015

作者：王馨[1];丁高恒[2];王宏宗[1];魏兴民[1];吴建军[1];迟婷[2];白晓蓉[2];刘玉琴[2]

第一作者：王馨

机构：[1]甘肃中医药大学公共卫生学院数学与统计学教研室,兰州730000;[2]甘肃省肿瘤医院肿瘤流行病学研究中心,兰州730050

第一机构：甘肃中医药大学公共卫生学院

年份：2022

卷号：14

期号：1

起止页码：99

中文期刊名：中国癌症防治杂志

外文期刊名：CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT

收录：CSTPCD

基金：甘肃省科技厅技术创新引导计划项目(18CX1ZA008);甘肃卫生行业科研计划项目(GSWST2011-14);西北营养与环境相关疾病中医药防控“2011协同创新中心”开放基金(ZYXT-20-03)。

语种：中文

中文关键词：乳腺癌;发病率;死亡率;肿瘤登记;变化趋势;甘肃

外文关键词：Breast cancer;Incidence;Mortality;Cancer registration;Change trend;Gansu

摘要：目的分析2009—2015年甘肃省肿瘤登记地区女性乳腺癌发病和死亡情况及变化趋势。方法根据甘肃省肿瘤登记地区上报的2009—2015年乳腺癌数据,计算粗发病(死亡)率、年龄别发病(死亡)率、累积率(0~74岁)、标化发病(死亡)率。中国人口标化率(中标率)根据2000年全国普查标准人口年龄构成计算,世界人口标化率(世标率)依照Segi's世界标准人口构成计算。运用Joinpoint 4.7统计软件计算年度变化百分比(annual percent change,APC)。结果2009—2015年甘肃省肿瘤登记地区乳腺癌新发病例4980例,粗发病率为27.14/10万,中标率为22.84/10万,世标率为23.56/10万;乳腺癌死亡病例895例,粗死亡率为8.72/10万,中标率为7.61/10万,世标率为8.00/10万,城市地区乳腺癌粗发病率为28.59/10万,中标率为23.69/10万,世标率为24.54/10万;农村地区粗发病率为24.27/10万,中标率为22.08/10万,世标率为22.15/10万。城市地区乳腺癌粗死亡率为10.13/10万,中标率为8.34/10万,世标率为8.71/10万;农村地区粗死亡率为4.70/10万,中标率为5.79/10万,世标率为6.15/10万。年龄别发病高危人群为50~岁年龄组,年龄别死亡高危人群为80~岁年龄组,且年龄别发病率、死亡率均随年龄增长而升高。2009—2015年甘肃省乳腺癌中标发病率(APC=-3.8%,95%CI:-10.5%~3.5%)和中标死亡率(APC=-10.1%,95%CI:-24.9%~7.6%)总体略有下降,但趋势变化无统计学意义(P>0.05)。结论2009—2015年甘肃省女性乳腺癌发病率和死亡率变化趋势平稳,但城市地区的发病和死亡水平高于农村地区,且中老年人群为高危人群。
ObjectiveTo analyze the incidence and mortality of female breast cancer in the registration areas of Gansu province from2009 to 2015.MethodsThe crude incidence(mortality)rate,age-specific incidence(mortality)rate,cumulative rate(0-74 years old)and standardized incidence(mortality)rate were calculated based on the breast cancer data reported by the cancer registration areas in Gansu province from 2009 to 2015.The age standardized rates were calculated according to the Chinese population census in 2000(ASR China)and Segi's standard population(ASR world).The annual percent change(APC)was calculated by Joinpoint 4.7 software.ResultsA total of 4,980 new cases of breast cancer were reported in cancer registration areas of Gansu province from 2009 to 2015 with a crude incidence rate of 27.14/105,the ASR China of 22.84/105,and the ASR world of 23.56/105.There were 895 deaths by breast cancer,the crude mortality rate was 8.72/105,the ASR China was 7.61/105,and the ASR world was 8.00/105.The crude incidence rate of breast cancer in urban area was 28.59/105,the ASR China was 23.69/105,and the ASR world was 24.54/105.The crude incidence rate in rural area was 24.27/105,the ASR China was 22.08/105,and the ASR world was 22.15/105.The crude mortality rate of breast cancer in the urban area was 10.13/105,the ASR China was 8.34/105,and the ASR world was 8.71/105.The crude mortality rate of breast cancer in rural area was 4.70/105,the ASR China was 5.79/105,and the ASR world was 6.15/105.The high risk group of age-specific incidence was the 50-year old group,and the high risk group of age-specific mortality was the 80-year old group,and the age-specific incidence and mortality rates increased with age.From 2009 to 2015,the incidence(APC=-3.8%,95%CI:-10.5%to 3.5%)and mortality(APC=-10.1%,95%CI:-24.9%to 7.6%)of ASR China of breast cancer in Gansu province decreased slightly,but the change of trend was not statistically significant(P>0.05).ConclusionsFrom 2009 to 2015,the trend of female breast cancer incidence and mortality in Gansu province was stable,but the incidence and mortality in urban areas were higher than those in rural areas,and the middle-aged and elderly women were high-risk groups.