文献类型：期刊文献

英文题名：Laboratory indices in patients with osteonecrosis of the femoral head: a retrospective comparative study

作者：Zheng, Haotian[1];Ye, Binglin[2];Huang, Kesong[3];Gao, Xiangming[4];Chen, Wei[2,3]

第一作者：Zheng, Haotian

通信作者：Chen, W[1];Chen, W[2]

机构：[1]Heilongjiang Univ Chinese Med, Affiliated Hosp 2, Harbin, Peoples R China;[2]Tradit Chinese Med Hosp Gansu Prov, Dept Orthopaed, Qilihe Dist Guazhou St 418, Lanzhou 730050, Gansu, Peoples R China;[3]Gansu Univ Chinese Med, Lanzhou 730030, Gansu, Peoples R China;[4]Puyang Med Coll, Puyang 457000, Henan, Peoples R China

第一机构：Heilongjiang Univ Chinese Med, Affiliated Hosp 2, Harbin, Peoples R China

通信机构：[1]corresponding author), Tradit Chinese Med Hosp Gansu Prov, Dept Orthopaed, Qilihe Dist Guazhou St 418, Lanzhou 730050, Gansu, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Lanzhou 730030, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2023

卷号：18

期号：1

外文期刊名：JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH

收录：;Scopus(收录号：2-s2.0-85173139628);WOS:【SCI-EXPANDED(收录号:WOS:001083573200005)】；

基金：We appreciate the technical support provided by our hospital.

语种：英文

外文关键词：Femoral head necrosis; Routine blood; Biochemical Indicators; Retrospective cases; Risk factors

摘要：BackgroundOsteonecrosis of the femoral head is a degenerative condition linked to corticosteroids, alcoholism, or trauma. With its rising prevalence due to increased hormone drug use and its debilitating effects on young to middle-aged individuals, understanding its association with specific laboratory indicators can aid early diagnosis and prevention.MethodsUpon retrospective analysis of the clinical data pertaining to individuals diagnosed with femoral head necrosis, spanning from January 2016 to January 2022, a comprehensive evaluation was conducted within the same time frame. The study aimed to ascertain the presence of femoral head necrosis in a total of 1176 individuals. A total of 1036 healthy patients were recruited randomly, ensuring that their ages matched. The risk variables associated with the utilization of logistic regression analysis and analysis techniques are employed. The patient examines the age distribution within a specific age group.ResultsThe levels of high-density lipoprotein, low-density lipoprotein A1, lipoprotein B1, total protein, albumin, globulin, and other lipophilic metabolism and coagulation markers exhibited a statistically significant increase compared to the control group. A multifactor logistic regression analysis was conducted to identify potential risk factors associated with femoral head necrosis in patients.ConclusionFemoral head necrosis is associated with a range of variables including coagulation malfunction, lipid metabolic abnormalities, and inflammation.