文献类型：期刊文献

中文题名：新生化颗粒给药时间和剂量对药物流产结局的影响

英文题名：Administration Time and the Dosage of Xin ShengHua Granules Influencing on Abortion Outcome

作者：谢知慧[1];赵粉琴[1]

第一作者：谢知慧

机构：[1]甘肃中医药大学,甘肃兰州730000

第一机构：甘肃中医药大学

年份：2016

卷号：29

期号：6

起止页码：73

中文期刊名：西部中医药

外文期刊名：Western Journal of Traditional Chinese Medicine

收录：CSTPCD

基金：甘肃省科技厅科学事业费项目计划(编号QSO12-C33-291004TCYA015)

语种：中文

中文关键词：早期妊娠;新生化颗粒;流产结局

外文关键词：early pregnancy; Xin Sheng Hua granules; abortion outcome

摘要：目的:观察新生化颗粒不同剂量、不同给药时间对早期妊娠药物流产结局的影响。方法:将158例患者随机分为观察组95例,对照组63例。2组均常规服用米非司酮、米索前列醇,观察组、对照组分别于口服米索前列醇后2小时、24小时开始口服新生化颗粒,用量均为4袋/次,3次/d,连续7天。结果:完全流产率观察组为94.7%,对照组为64.6%,2组比较差异有统计学意义(P<0.05)。阴道出血时间、出血量2组比较差异有统计学意义(P<0.05)。结论:足量早期使用大剂量新生化颗粒可提高完全流产率、减少阴道出血时间和出血量。
Objective： To observe the effects of Xin Sheng Hua granules in different dosages at different administration times influencing on drug abortion outcomes of early pregnancy. Methods： All 158 patients were randomly allocated to 95 cases of the observation group and 63 cases of the control group. Both groups began to take mifepristone and misoprostol, the observation group and the control gronp took Xin Sheng Hua granules in two hours and 24 hours after they accepted oral administration of misoprostol, four packages each time, three times per day, for seven days consecutively. Results： Complete abortion rate of the observation group was 94.7%, higher than 64.6% of the control group, and the difference had statistical meaning in the comparison between both groups（P〈0.05）. The difference showed statistical meaning in the comparisons of vaginal bleeding time and bleeding amounts between both groups（P〈0.05）. Conclusion： Early use and enough Xin Sheng Hua granules could improve complete abortion rate, reduce vaginal bleeding time and bleeding amounts.