文献类型：期刊文献

英文题名：Gaining insights into nutrient and metal element distributions in radix Angelicae sinensis using mass spectrometry

作者：He, Shiyu[1,2];Li, Boyan[1,2];Wang, Lan[3];Wang, Zihan[1,2];Zhang, Jin[1,2];Hu, Yun[4];Wang, Yali[5]

第一作者：He, Shiyu

通信作者：Li, BY[1];Li, BY[2];Hu, Y[3]

机构：[1]Guizhou Med Univ, Sch Publ Hlth, Key Lab Endem & Ethn Dis, Minist Educ, Guiyang 561113, Peoples R China;[2]Guizhou Med Univ, Key Lab Med Mol Biol Guizhou Prov, Guiyang 561113, Peoples R China;[3]Guizhou Med Univ, Inst Med Sci, Guiyang 550000, Peoples R China;[4]China Tobacco Guizhou Ind Co Ltd, Technol Ctr, Guiyang 550009, Peoples R China;[5]Gansu Univ Chinese Med, Sch Pharm, Lanzhou 730000, Peoples R China

第一机构：Guizhou Med Univ, Sch Publ Hlth, Key Lab Endem & Ethn Dis, Minist Educ, Guiyang 561113, Peoples R China

通信机构：[1]corresponding author), Guizhou Med Univ, Sch Publ Hlth, Key Lab Endem & Ethn Dis, Minist Educ, Guiyang 561113, Peoples R China;[2]corresponding author), Guizhou Med Univ, Key Lab Med Mol Biol Guizhou Prov, Guiyang 561113, Peoples R China;[3]corresponding author), China Tobacco Guizhou Ind Co Ltd, Technol Ctr, Guiyang 550009, Peoples R China.

年份：2025

外文期刊名：ANALYTICAL METHODS

收录：;EI(收录号：20251318137539);Scopus(收录号：2-s2.0-105002566095);WOS:【SCI-EXPANDED(收录号:WOS:001451933800001)】；

基金：This work was supported by the National Natural Science Foundation of China (Grant No. 82060712 and 82360700), the Guizhou Provincial Science and Technology Projects (Grant No. [2018]1130), and the Key R&D Program of Science and Technology Department of Gansu Province, China (Grant No. 20YF8NA067).

语种：英文

外文关键词：Inductively coupled plasma mass spectrometry

摘要：Angelica sinensis is a medicine food homology plant. Its dried root (radix Angelicae sinensis, RAS) is rich in nutrients and bioactive ingredients. This study involved a quantitative analysis of 401 RAS material batches harvested from different geographical regions over a time span of four years. Quantitative statistical distributions of 24 nutrients of interest were determined using ultrahigh performance liquid chromatography-tandem mass spectrometry. The distribution features of 15 target metal elements were specified using inductively coupled plasma-mass spectrometry and atomic absorption spectroscopy methods. A new integrated bioaccessibility response method was introduced to address the statistical analysis of content responses of multiple nutrients through one multivariate compact area. This work not only provides new insights into the compositional ingredients of RAS material to assist in quality control but also helps in understanding the potential benefits of RAS material to human health and increasing its applications.