文献类型：期刊文献

中文题名：双水平气道正压通气治疗慢性阻塞性肺疾病合并阻塞性睡眠呼吸暂停低通气综合征有效性的Meta分析

英文题名：A meta-analysis of the effectiveness of bi-level positive airway pressure on chronic obstructive pulmonary disease with obstructive sleep apnea hypopnea syndrome

作者：魏才杰[1];夏晓黎[2];张宁[1];马艳萍[2];王亚锋[1];马娇娇[1];张帆[2]

第一作者：魏才杰

机构：[1]甘肃中医药大学中西医结合学院,甘肃兰州730099;[2]甘肃中医药大学附属医院,甘肃兰州730000

第一机构：甘肃中医药大学中西医结合学院

年份：2022

卷号：14

期号：29

起止页码：130

中文期刊名：中医临床研究

外文期刊名：Clinical Journal Of Chinese Medicine

基金：甘肃省中医药管理局立项课题(GZK-2019-33);甘肃中医药大学附属医院技术创新立项课题(gzfy-2020-09);兰州市科技发展指导性计划项目(2020-ZD-63)。

语种：中文

中文关键词：双水平气道正压通气;慢性阻塞性肺疾病;阻塞性睡眠呼吸暂停低通气综合征;Meta分析

外文关键词：Bi-level positive airway pressure;Chronic obstructive pulmonary disease;Obstructive sleep apnea hypopnea syndrome;Meta-analysis

摘要：目的:运用系统评价方式探讨双水平气道正压通气(Bi-level Positive Airway Pressure,BiPAP)治疗慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)合并阻塞性睡眠呼吸暂停低通气综合征(Obstructive Sleep Apnea Hypopnea Syndrome,OSAHS)的有效性。方法:计算机检索中国知网、中国生物医学文献数据库、万方数据库、维普数据库、The Cochrane Library、Web of Science、PubMed、Embase等数据库,检索与BiPAP治疗COPD合并OSAHS相关的随机对照试验,采用RevMan 5.3对其进行Meta分析。结果:15篇文献符合纳入标准,Meta分析结果显示,BiPAP可显著改善COPD合并OSAHS患者的第1秒用力呼气容积(Forced Expiratory Volume in 1 Second,FEV_(1))占用力肺活量(Forced Vital Capacity,FVC)的百分比(FEV_(1)/FVC%)、氢离子浓度指数(pH)、动脉血氧分压(Partial Pressure of Oxygen,PaO_(2))、动脉血二氧化碳分压(Partial Pressure of Carbon Dioxide,PaCO_(2))、呼吸暂停低通气指数(Apnea Hypopnea Index,AHI)指标。结论:BiPAP可显著改善COPD合并OSAHS患者的FEV_(1)/FVC%、pH、PaO_(2)、PaCO_(2)、AHI指标,临床合理应用可显著改善患者的预后。
Objective:To explore the effectiveness of BiPAP in the treatment of COPD with OSAHS by a systematic evaluation.Methods:On CNKI,SinoMed,Wanfang data,VIP database,the Cochrane Library,Web of Science,PubMed,Embase databases,the related literature was searched by computer to retrieve randomised controlled trials of treating overlap syndrome by BiPAP.RevMan 5.3 software was used to perform a meta-analysis.Results:A total of 15 studies met the inclusion criteria.The results of the meta-analysis showed that BiPAP could significantly ameliorate the indicators of FEV_(1)/FVC%,pH,PaO_(2),PaCO_(2) and AHI of COPD patients with OSAHS.Conclusion:BiPAP can significantly ameliorate the indicators of FEV_(1)/FVC%,pH,PaO_(2),PaCO_(2) and AHI in COPD patients with OSAHS,and its clinically rational application can significantly ameliorate the prognosis of patients.