文献类型：期刊文献

中文题名：盐酸多奈哌齐联合西酞普兰治疗青中年脑梗死患者抑郁及认知功能障碍临床疗效分析

英文题名：Clinical efficacy analysis of donepezil hydrochloride combined with citalopram in the treatment of depression and cognitive dysfunction in young and middle-aged cerebral infarction patients

作者：唐珂[1];高丽波[1];彭晓明[1]

第一作者：唐珂

机构：[1]甘肃中医药大学附属医院脑病科,甘肃兰州730000

第一机构：甘肃中医药大学第二附属医院

年份：2020

卷号：0

期号：5

起止页码：62

中文期刊名：心理月刊

语种：中文

中文关键词：青中年脑梗死;焦虑;抑郁;认知功能;盐酸多奈哌齐;西酞普兰

外文关键词：Middle-aged cerebral infarction;anxiety;depression;cognitive function;donepezil hydrochloride;citalopram

摘要：目的分析针对青中年脑梗死患者给予盐酸多奈哌齐联合西酞普兰进行治疗后对其抑郁及认知功能障碍的影响效果。方法随机抽取2016年~2018年本院收治的100例青中年脑梗死患者为研究对象,通过随机表数字的方法选出一号组(n=50)和二号组(n=50)。对比两组治疗后的焦虑、抑郁及神经功能缺损评分。结果一号组治疗后的焦虑、抑郁及神经功能缺损评分显著高于二号组(P<0.05)。结论在青中年脑梗死患者的临床治疗中,给予盐酸多奈哌齐联合西酞普兰进行治疗效果良好,能够有效改善患者的焦虑抑郁情绪,有利于提高患者的认知功能。
Objective To analyze the effects of donepezil hydrochloride combined with citalopram on depression and cognitive dysfunction in patients with middle-aged cerebral infarction. Methods 100 young and middle-aged cerebral infarction patients admitted to our hospital from 2016 to 2018 were randomly selected as the study objects, according to the random table number method, they were divided into group one(n=50) and group two(n=50). The scores of anxiety, depression and neurological deficit were compared between the two groups. Results The scores of anxiety, depression and neurological deficit in group one were significantly higher than those in group two(P<0.05). Conclusion In the clinical treatment of patients with cerebral infarction in middle and young age, the treatment with donepezil hydrochloride combined with citalopram is effective, which can effectively improve the anxiety and depression of patients and improve the cognitive function of patients.