文献类型：期刊文献

英文题名：Br?nsted Acid-Catalyzed Intramolecular Tandem Double Cyclization of γ-Hydroxy Acetylenic Ketones with Alkynes into Naphtho[1,2-b]furan-3-ones

作者：Zhang, Sen[1]; Zhu, Hai-Tao[1]; Xi, Jia-Jun[1]; Wang, San-Bao[1]; Chang, Xin[1]; Shen, Cheng-Ping[1]; Feng, Yue[1]; Zhang, Zhao-Yang[1]; Zhao, Meng-Ting[1]; Zhang, Li-Kun[1]; Li, Mi[2]; Jin, Xiaojie[2]; Zhou, An-Xi[3]; Zhou, Ni-Ni[1]

第一作者：Zhang, Sen

机构：[1] College of Chemistry and Chemical Engineering, Shannxi Key Laboratory of Phytochemistry, Baoji University of Arts and Sciences, Baoji, 721013, China; [2] Gansu University Key Laboratory for Molecular Medicine, Chinese Medicine Prevention and Treatment of Major Diseases, Gansu University of Chinese Medicine, Lanzhou, 730000, China; [3] key Laboratory of Applied Organic Chemistry, Higher Institutions of Jiangxi Province, Shangrao Normal University, Shangrao, 334000, China

第一机构：College of Chemistry and Chemical Engineering, Shannxi Key Laboratory of Phytochemistry, Baoji University of Arts and Sciences, Baoji, 721013, China

通信机构：[1]College of Chemistry and Chemical Engineering, Shannxi Key Laboratory of Phytochemistry, Baoji University of Arts and Sciences, Baoji, 721013, China;[2]Gansu University Key Laboratory for Molecular Medicine, Chinese Medicine Prevention and Treatment of Major Diseases, Gansu University of Chinese Medicine, Lanzhou, 730000, China;[1]College of Chemistry and Chemical Engineering, Shannxi Key Laboratory of Phytochemistry, Baoji University of Arts and Sciences, Baoji, 721013, China|[10735]甘肃中医药大学;

年份：2024

卷号：89

期号：3

起止页码：1633

外文期刊名：Journal of Organic Chemistry

收录：EI(收录号：20240415449720);Scopus(收录号：2-s2.0-85183163353)

语种：英文

外文关键词：Aromatic compounds - Catalysis - Hydrocarbons - Ketones - Organic pollutants

摘要：A metal-free and atom-economic route for the synthesis of naphtho[1,2-b]furan-3-ones has been realized via p-TsOH·H2O-catalyzed intramolecular tandem double cyclization of γ-hydroxy acetylenic ketones with alkynes in formic acid. The benzene-linked furanonyl-ynes are the key intermediates obtained by the scission/recombination of C-O double bonds. Further, the structural modifications of the representative product were implemented by reduction, demethylation, substitution, and [5 + 2]-cycloaddition. ? 2024 American Chemical Society.