文献类型：期刊文献

英文题名：Efficacy and safety of prophylactic intraoperative sac embolization in EVAR for abdominal aortic aneurysm: A meta-analysis

作者：Chen, Quan[1];Zhang, Yuan[2];Lei, Kangqing[2];Fu, Liangyin[2];Zhang, Dengxiao[2];Sun, Wanli[3];Shi, Chaohai[3];Niu, Qibing[3]

第一作者：Chen, Quan

通信作者：Niu, QB[1]

机构：[1]Dongguan Peoples Hosp, Dept Intervent & Vasc Surg, Dongguan, Guangdong, Peoples R China;[2]Gansu Univ Chinese Med, Gansu Prov Hosp, Clin Med Coll 1, Lanzhou, Gansu, Peoples R China;[3]Gansu Prov Hosp, Dept Vasc Surg, Lanzhou, Gansu, Peoples R China

第一机构：Dongguan Peoples Hosp, Dept Intervent & Vasc Surg, Dongguan, Guangdong, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Vasc Surg, Lanzhou, Gansu, Peoples R China.

年份：2023

卷号：9

外文期刊名：FRONTIERS IN SURGERY

收录：;Scopus(收录号：2-s2.0-85146578702);WOS:【SCI-EXPANDED(收录号:WOS:000918857100001)】；

语种：英文

外文关键词：abdominal aortic aneurysm; endovascular aneurysm repair; embolization; type II endoleak; SAC

摘要：Objective: We aimed to investigate the effectiveness and safety of prophylactic sac embolization during endovascular aneurysm repair (EVAR) in patients suffering from abdominal aortic aneurysms.Methods: We performed a systematic literature search of PubMed, Web of Science, EMbase, Cochrane Library, China National Knowledge Infrastructure (CNKI), VIP, Wanfang and China Biomedical Literature Database (CBM) to identify studies evaluating the outcomes of sac embolization vs. no embolization among patients who had received EVAR. The time limit of the search was from the establishing database to July 22, 2022. Outcome measures involved the type II endoleak rate, the other endoleak rate, the reintervention rate, mortality, and operation time. Fixed (no heterogeneity) or random effects models were constructed for each outcome. The outcomes are represented as the odds ratio (OR) with a 95% confidence interval (CI).Results: Among the 2,622 studies screened, 13 studies involving 747 participants were included in the review. The incidence of early-term type II endoleak (OR = 0.2, 95% CI (0.13,0.31), P < 0.00001), mid-term type II endoleak (OR = 0.23, 95% CI (0.15,0.37), P < 0.00001), late-term type II endoleak (OR = 0.27, 95% CI (0.16,0.46), P < 0.00001) and reintervention (OR = 0.50, 95% CI (0.37,0.78), P = 0.002) within the sac embolization group were significantly lower than those in the non-embolization group. No significant differences were observed between the two groups were found for the other endoleak rates (OR = 0.67, 95% CI (0.34,1.32), P = 0.25), mortality (OR = 0.64, 95% CI (0.25,1.66), P = 0.36) and operation time operation (MD = 5.76, 95% CI (-8.30,19.83), P = 0.42).Conclusions: EVAR combined with sac embolization effectively reduces the incidence of type II endoleak and the reintervention rate without enhancing the operation time. Therefore, more high-quality studies are still needed for validation due to the limited amount and quality of included literature.