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基于脾主运化探析健脾益气类中药调节脾气虚机体代谢紊乱的研究进展     被引量:5

Regulation of Metabolic Disorders in Piqixu(脾气虚) by Jianpi(健脾) Yiqi(益气) Chinese Medicine Based on the Principle of Pizhuyunhua(脾主运化):A Review

文献类型:期刊文献

中文题名:基于脾主运化探析健脾益气类中药调节脾气虚机体代谢紊乱的研究进展

英文题名:Regulation of Metabolic Disorders in Piqixu(脾气虚) by Jianpi(健脾) Yiqi(益气) Chinese Medicine Based on the Principle of Pizhuyunhua(脾主运化):A Review

作者:宋沁洁[1];李国峰[1];李咸慰[1];吴红伟[1];李东辉[1];杨新荣[1];李越峰[1,2]

第一作者:宋沁洁

机构:[1]甘肃中医药大学,兰州730000;[2]甘肃省中药制药工艺工程研究中心,兰州730000

第一机构:甘肃中医药大学

年份:2023

卷号:39

期号:2

起止页码:115

中文期刊名:中药药理与临床

外文期刊名:Pharmacology and Clinics of Chinese Materia Medica

收录:北大核心:【北大核心2020】;CSCD:【CSCD2023_2024】;

基金:国家自然科学基金资助项目(编号:81460611、81960713、82160750);甘肃省教育厅产业支撑计划项目(编号:2021CYZC-21);甘肃省中药制药工艺工程研究中心开放课题(编号:ZYGY202003);科技创新服务平台建设项目-甘肃省道地中药材种质资源库(编号:18JR2TA017);中央引导地方科技发展专项资金项目-甘肃本草众智中医药文化传承创新创业试验实践基地(编号:30440323);甘肃省高等学校产业支撑计划项目-四种道地陇药绿色规范化产业发展示范推广(编号:2020C-09);民生科技专项(科技特派员专题)-中药材引种驯化与道地药材产业化扶贫示范推广(编号:20CX9NA070);甘肃省科学技术厅-科技计划(创新基地与人才计划)基础研究创新群体项目(编号:21JR7RA569);双一流科研重点项目(编号:GSSYLXM-05)。

语种:中文

中文关键词:脾气虚;健脾益气;机体代谢;研究进展

外文关键词:Piqixu(脾气虚);Jianpi(健脾)Yiqi(益气);Organismmetabolism;Research progress

摘要:中医理论提及脾主运化,脾功能失司常会导致机体糖代谢、蛋白质代谢、能量代谢、脂代谢、等发生紊乱,造成机体的物质能量代谢异常,进而引发高血压、血糖异常、血脂紊乱、肥胖症、非酒精性脂肪肝、Ⅱ型糖尿病、等代谢性疾病。临床上常用黄芪、人参、四君子汤、补中益气汤等健脾益气方药治疗脾气虚证。近年来,诸多学者通过研究表明脾气虚证机体存在代谢异常,且通过健脾益气类中药干预可调整代谢。本文从脾气虚与机体代谢紊乱关系、健脾益气类中药调节脾气虚机体代谢紊乱的研究现状进行综述,为阐明健脾益气类中药调节脾气虚机体代谢紊乱的可能机制提供参考。
According to the Pizhuyunhua(脾主运化)in traditional Chinese medicine,the malfunction of Pi(脾)will lead to metabolic disorders of glucose,protein,energy,and lipid,further resulting in metabolic diseases such as hypertension,pathoglycemia,dyslipidemia,obesity,non-alcoholic fatty liver,and type II diabetes.In clinical settings,Jianpi(健脾)Yiqi(益气)medicines,such as Huangqi(黄芪),Renshen(人参),Sijunzi(四君子)Decoction,and Buzhong Yiqi(补中益气)Decoction,are commonly used to treat Piqixu(脾气虚)syndrome.Inrecent years,metabolic disorders have been frequently verified in Piqixu syndrome and Jianpi Yiqi Chinese medicines can be used to regulate the disorders.This paper reviews the relationship between Piqixu and metabolic disorders and the regulation of metabolic disorders in Piqixu by Jianpi Yiqi Chinese medicines,which is expected to serve as a reference for elucidating the mechanism underlying the alleviation of metabolic disorders in Piqixu by Jianpi Yiqi Chinese medicines.

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