文献类型：期刊文献

英文题名：Investigation of antibacterial activity of one-dimensional electrospun Walnut green husk extract-PVP nanofibers

作者：Wang, Ning[1,2];Liu, Zhenlin[1,3];Yang, Jing[1,4];Song, Yingying[1]

第一作者：Wang, Ning;王宁

通信作者：Yang, J[1];Yang, J[2]

机构：[1]Gansu Anal & Res Ctr, Lanzhou 730000, Peoples R China;[2]Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730000, Peoples R China;[3]Lanzhou Univ, Key Lab Magnetism & Magnet Mat, Minist Educ, Lanzhou 730000, Peoples R China;[4]Gen Hosp PLA, Hosp 96604, Dept Infect Dis, Lanzhou 730000, Peoples R China

第一机构：Gansu Anal & Res Ctr, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Gansu Anal & Res Ctr, Lanzhou 730000, Peoples R China;[2]corresponding author), Gen Hosp PLA, Hosp 96604, Dept Infect Dis, Lanzhou 730000, Peoples R China.

年份：2022

卷号：31

期号：6

起止页码：779

外文期刊名：IRANIAN POLYMER JOURNAL

收录：;EI(收录号：20220911721503);Scopus(收录号：2-s2.0-85125274086);WOS:【SCI-EXPANDED(收录号:WOS:000758973900001)】；

基金：This project was funded by the Science and Technology Department of Gansu Province, China (20YF8FA015), 2021 Gansu Province Longyuan Youth Innovation and Entrepreneurship Talent (Team) Project, Organization Department of the Gansu Provincial Committee, China.

语种：英文

外文关键词：Walnut green husks; Extract; One-dimensional nanofibers; Electrospinning; Antibacterial activity; Environmentally friendly

摘要：As a by-product of walnuts crops, the clinical therapeutic effect of Walnut green husks has already been proven. In this work, with 95% ethanol and ultrasonicwave extraction technology to extract the Walnut green husks, by electrospinning technology, successfully prepared PVP fiber membranes with different concentrations of the extract. The properties of those diverse fibers were analyzed by Conductometry meter, Scanning electron microscopy (SEM), Fourier Transform infrared spectroscopy (FT-IR), and X-Ray Diffraction (XRD). The results show that the average diameter of nanofibers decreases and the electrical conductivity increases with the increase of the crude extract content of walnut green husk. For the FT-IR analysis, there were obvious characteristic absorption peaks of Juglone (5-hydroxy1,4-naphthoquinone) on the fibers. Furthermore, an antibacterial experiment on Escherichia coli revealed that the Walnut green husks loaded on the nanofiber membranes with different extract concentrations all have antibacterial effects, and the size of the inhibition zone increased with the decrease of the diameter of the diameter of the nanofiber and the increase of the Walnut green husks' extracts loaded, thereby proving potential strategies to develop drug delivery system. At the same time, only ethanol reagent is used in the polymer use process, and the experimental process is environmentally friendly, thereby reducing the pollution of organic reagents and expanding the idea of green application of polymers.