文献类型：期刊文献

英文题名：Clinical effect of modified drug and small splint fixation on osteoporotic proximal humeral fractures

作者：Zhang, Hongwei[1,2];Quan, Zhen[1];Zhao, Xiyun[1,2];Wang, Zhipeng[2];Li, Yuanzhen[2];Zhang, Xiaogang[2]

第一作者：张宏伟

通信作者：Zhang, HW[1]

机构：[1]Gansu Univ Chinese Med, Clin Coll Chinese Med, Lanzhou, Gansu, Peoples R China;[2]Gansu Univ Chinese Med, Affiliated Hosp, Intervertebral Disc Ctr, 732 Jiayuguan West Rd, Lanzhou 730020, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, Intervertebral Disc Ctr, 732 Jiayuguan West Rd, Lanzhou 730020, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：13

期号：12

起止页码：9948

外文期刊名：INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000605020700099)】；

语种：英文

外文关键词：Modified drug small splint fixation; osteoporosis; humerus; fractures

摘要：Objective: To explore the clinical effect of a modified drug and small splint fixation in the treatment of osteoporotic proximal humeral fractures. Methods: Eighty-six patients with osteoporotic proximal humeral fractures were included in this study and randomly divided into an observation group (43 cases) and a control group (43 cases). Patients in the observation group were treated with Xiaoding ointment combined with modified small splint fixation, while those in the control group were treated with locking plate fixation. The shoulder joint function (Constant-Murley and Neer scores) of patients in the two groups were compared one year after treatment. The time of callus appearance, fracture healing, swelling resolution and hospitalization were analyzed, as well as shoulder joint function recovery and complications. The changes of Visual Analogue Scale (VAS) and EuroQol five dimensions questionnaire (EQ-5D) scores before and 3, 6, and 12 months after treatment were compared between the two groups. Results: No significant differences were observed in Constant-Murley and Neer scores and excellent and good rate of shoulder joint function between the two groups (P > 0.05). Compared with the control group, the time of callus appearance, fracture healing, swelling resolution and hospitalization time were all shorter in the observation group (P < 0.001). After treatment, there were 2 cases of infection, 1 case of ischemic necrosis of the femoral head and 3 cases of screw penetration in the control group, with a complication rate of 13.95%. Whereas, no complication was observed in the observation group, and the difference between the two groups was statistically significant (P = 0.026). The VAS and EQ-5D scores did not differ statistically between the two groups before and 12 months after treatment (P > 0.05). At 3 and 6 months after treatment, the VAS score decreased while the EQ-5D score increased in both groups; compared with the control group, the VAS score was significantly lower and the EQ-5D score was significantly higher in the observation group (all P < 0.05). Conclusion: Modified drug and small splint fixation for the treatment of osteoporotic proximal humeral fractures can significantly improve shoulder joint function, relieve pain and accelerate fracture healing, with a low incidence of complications.