文献类型：期刊文献

中文题名：超滤对身痛逐瘀汤活血化瘀效果的影响

英文题名：Effects of Ultrafiltration Process on Activating Blood and Removing Stasis Efficacy of Shentong Zhuyu Decoction

作者：刘晓霞[1];王继龙[1];魏舒畅[1];宋晓春[1];金辉[1]

第一作者：刘晓霞

机构：[1]甘肃中医药大学,甘肃兰州730000

第一机构：甘肃中医药大学

年份：2016

卷号：23

期号：1

起止页码：86

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2015_2016】；

基金：甘肃省高校基本科研费项目(BH2012-018)

语种：中文

中文关键词：身痛逐瘀汤;超滤;活血化瘀;小鼠

外文关键词：Shentong Zhuyu Decoction;;ultrafiltration process;;activating blood and removing stasis;;mice

摘要：目的研究超滤对身痛逐瘀汤活血化瘀效果的影响,考察超滤技术用于身痛逐瘀汤纯化的可行性。方法以小鼠微血管动静脉管径、小鼠凝血时间、耳廓循环障碍小鼠毛细血管开放量为评价指标,考察身痛逐瘀汤提取液未超滤及不同超滤方法对活血化瘀效果的影响。结果身痛逐瘀汤具有较好的活血化瘀效果,20、50 nm膜超滤液与未滤液相比其活血化瘀效果无明显差异。结论超滤技术可用于身痛逐瘀汤的纯化工艺,所选膜孔径应不小于20 nm。
Objective To study the effects of ultrafiltration process on activating blood and removing blood stasis efficacy ofShentong Zhuyu Decoction; To investigate the feasibility of applying ultrafiltration technology in purifying Shentong Zhuyu Decoction.Methods The mice micro artery and vein diameter, clotting time and opening capillary of auricle microcirculation of mice were used as indexes to observe the effects of different ultrafiltration process on activating blood and removing blood stasis efficacy ofShentong Zhuyu Decoction.ResultsShentong Zhuyu Decoction showed satisfying efficacy of activating blood and removing blood stasis. There was no significant difference between the non-ultrafiltration process and ultrafiltration processed by 20 and 50 nm ultrafiltration membranes.Conclusion Ultrafiltration technology can be applied to purifying Shentong Zhuyu Decoction, and the membrane pore size must be more than 20 nm.