文献类型：期刊文献

英文题名：Analysis of the safety and feasibility of subcutaneous areolar tunnel single-port thoracoscopic radical resection for lung cancer: a retrospective cohort study

作者：Yang, Kai[1,2];Li, Keyong[1,2];Guo, Chao[1,3];Que, Changhao[1,2];Zuo, Zhuang[1,2];Wang, Jin[1,2];Wang, Qi[1,2];Jin, Dacheng[2];Gou, Yunjiu[2];Wang, Chengfeng[2]

第一作者：Yang, Kai;杨昆;杨魁

通信作者：Gou, YJ[1];Wang, CF[1]

机构：[1]Gansu Univ Chinese Med, Clin Med Sch 1, Lanzhou 730000, Peoples R China;[2]Gansu Prov Hosp, Dept Thorac Surg 1, Lanzhou 730000, Peoples R China;[3]Gansu Prov Peoples Hosp, Dept Crit Care Med, Lanzhou 730000, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Thorac Surg 1, Lanzhou 730000, Peoples R China.

年份：2026

外文期刊名：UPDATES IN SURGERY

收录：;Scopus(收录号：2-s2.0-105034836032);WOS:【SCI-EXPANDED(收录号:WOS:001733630000001)】；

基金：This research is funded by the following project. The "Innovative Star" Project for Postgraduate Students of Gansu Provincial Department of Education (Project No. 2025CXZX-947). Key Research and Development Project of Gansu Provincial Department of Science and Technology (Project No. 22YF7FA095). The internal project of Gansu Provincial People's Hospital (Project No. 2024KYQDJ-A-3). The internal project of Gansu Provincial People's Hospital (Project No. 22GSSYC-9).

语种：英文

外文关键词：Video-assisted thoracoscopy; Lung cancer; Single-port thoracoscopy; Areola incision; Subcutaneous tunnel

摘要：This study aims to evaluate the surgical efficacy and safety of subareolar subcutaneous tunnel single-port thoracoscopic radical resection in the treatment of lung cancer. Retrospective analysis of 61 lung cancer patients undergoing resection: 29 received areola subcutaneous tunneling single-port resection, and 32 conventional single-port VATS. Perioperative param-eters, complications, and 1-month outcomes were compared. There were no statistically significant differences between the two groups with respect to intraoperative operation time, total number of lymph nodes dissected, postoperative drain-age duration, total postoperative drainage volume, length of postoperative hospital stay, VAS pain score on postoperative day 3, or incidence of postoperative complications (all P > 0.05). However, The periareolar incision group demonstrated significantly lower intraoperative blood loss (63.62 +/- 11.49 mL vs. 77.03 +/- 14.19 mL), lower VAS pain scores on the first postoperative day (3.69 +/- 1.49 vs. 4.88 +/- 1.72) and second postoperative day (3.31 +/- 1.39 vs. 4.28 +/- 1.76), and a lower rate of postoperative analgesic prescriptions (20.69% vs. 53.13%) compared to the single-port group (all P < 0.05). However, the periareolar approach was associated with longer surgical approach time (3.40 +/- 0.28 min vs. 1.68 +/- 0.27 min), pro-longed total operation duration (124.12 +/- 8.25 min vs. 118.21 +/- 9.28 min), and an increased incidence of subcutaneous fluid accumulation in the tunnel area (13.79% vs. 0%) (all P < 0.05). One areola-group conversion to open surgery occurred. No perioperative deaths or breast injuries were observed. Scarring and sensory disturbances were significantly reduced in the areola group. Areola subcutaneous tunneling single-port resection is safe and feasible, with perioperative outcomes comparable to conventional VATS. It reduces early postoperative pain and improves cosmesis but requires vigilance for tunnel-related fluid accumulation. This approach offers a viable option for patients prioritizing aesthetic outcomes. This study, being a retrospective analysis, is subject to certain limitations, including a limited sample size and a relatively short follow-up duration. Therefore, the conclusions drawn require further validation through large-scale, prospective studies with robust designs.