文献类型：期刊文献

英文题名：Automatic measurement of anatomical parameters of the lumbar vertebral body and the intervertebral disc on radiographs by deep learning

作者：Yao, Hongyan[1];Zhang, Zhihong[2];Cheng, Guohua[3];Chen, Xiaofei[4];He, Linyang[3];Wang, Wenqi[4];Zhou, Sheng[1];Wang, Ping[1]

第一作者：Yao, Hongyan

通信作者：Zhou, S[1];Wang, P[1]

机构：[1]Gansu Prov Hosp, Dept Radiol, 204 Donggang West Rd, Lanzhou 730000, Peoples R China;[2]Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[3]Hangzhou Jianpei Technol Co Ltd, Hangzhou, Peoples R China;[4]Gansu Prov Hosp Tradit Chinese Med, Dept Radiol, Lanzhou, Peoples R China

第一机构：Gansu Prov Hosp, Dept Radiol, 204 Donggang West Rd, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Radiol, 204 Donggang West Rd, Lanzhou 730000, Peoples R China.

年份：2024

卷号：14

期号：8

起止页码：5877

外文期刊名：QUANTITATIVE IMAGING IN MEDICINE AND SURGERY

收录：;Scopus(收录号：2-s2.0-85199939495);WOS:【SCI-EXPANDED(收录号:WOS:001312970900024)】；

基金：Funding: This work was supported by the National Natural Science Foundation of China (No. 82360358) ; the Lanzhou Talent Innovation and Entrepreneurship Project (No. 2020-RC-53) ; and Gansu Youth Science and Technology Fund Program (No. 23JRRA1774) .

语种：英文

外文关键词：Deep learning (DL); lateral lumbar radiograph; anatomical parameters; automatic measurement

摘要：Background: Lumbar spine disorders are one of the common causes of low back pain (LBP). Objective and reliable measurement of anatomical parameters of the lumbar spine is essential in the clinical diagnosis and evaluation of lumbar disorders. However, manual measurements are time-consuming and laborious, with poor consistency and repeatability. Here, we aim to develop and evaluate an automatic measurement model for measuring the anatomical parameters of the vertebral body and intervertebral disc based on lateral lumbar radiographs and deep learning (DL). Methods: A model based on DL was developed with a dataset consisting of 1,318 lateral lumbar radiographs for the prediction of anatomical parameters, including vertebral body heights (VBH), intervertebral disc heights (IDH), and intervertebral disc angles (IDA). The mean of the values obtained by 3 radiologists was used as a reference standard. Statistical analysis was performed in terms of standard deviation (SD), mean absolute error (MAE), Percentage of correct keypoints (PCK), intraclass correlation coefficient (ICC), regression analysis, and Bland-Altman plot to evaluate the performance of the model compared with the reference standard. Results: The percentage of intra-observer landmark distance within the 3 mm threshold was 96%. The percentage of inter-observer landmark distance within the 3 mm threshold was 94% (R1 and R2), 92% (R1 and R3), and 93% (R2 and R3), respectively. The PCK of the model within the 3 mm distance threshold was 94-99%. The model-predicted values were 30.22 +/- 3.01 mm, 10.40 +/- 3.91 mm, and 10.63 degrees +/- 4.74 degrees for VBH, IDH, and IDA, respectively. There were good correlation and consistency in anatomical parameters of the lumbar vertebral body and disc between the model and the reference standard in most cases (R-2=0.89-0.95, ICC =0.93-0.98, MAE =0.61-1.15, and SD =0.89-1.64). Conclusions: The newly proposed model based on a DL algorithm can accurately measure various anatomical parameters on lateral lumbar radiographs. This could provide an accurate and efficient measurement tool for the quantitative evaluation of spinal disorders.