文献类型：期刊文献

英文题名：Fatal pulmonary artery dissection in the setting of aneurysm and pulmonary hypertension: a case report and literature review

作者：Wang, Bowen[1];Zhang, Zhan[1];Chen, Ke[2];Qin, Yahong[1];Li, Chongwei[1];Xie, Ping[1];Gao, Jing[3,4,5]

第一作者：Wang, Bowen

通信作者：Xie, P[1];Gao, J[2];Gao, J[3];Gao, J[4]

机构：[1]Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou, Peoples R China;[2]Gansu Univ Tradit Chinese Med, 35 Dingxi East Rd, Lanzhou, Peoples R China;[3]Karolinska Inst, Dept Med Solna, Stockholm, Sweden;[4]Karolinska Univ Hosp, Ctr Mol Med, Stockholm, Sweden;[5]Univ Helsinki, Dept Resp Med, Helsinki, Finland

第一机构：Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Cardiol, 204 Donggang West Rd, Lanzhou, Peoples R China;[2]corresponding author), Karolinska Inst, Dept Med Solna, Stockholm, Sweden;[3]corresponding author), Karolinska Univ Hosp, Ctr Mol Med, Stockholm, Sweden;[4]corresponding author), Univ Helsinki, Dept Resp Med, Helsinki, Finland.

年份：2026

卷号：21

期号：1

外文期刊名：JOURNAL OF CARDIOTHORACIC SURGERY

收录：;Scopus(收录号：2-s2.0-105034454755);WOS:【SCI-EXPANDED(收录号:WOS:001721914100001)】；

基金：The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was supported by Gansu Provincial Natural Science Foundation (Funding Reference Number 23JRRA1287); Gansu Province Pharmaceutical Research Project (Funding Reference Number 2025GSMPA059); Gansu Province Joint Scientific Research Fund (Funding Reference Number 24JRRA886). Gansu Province Traditional Chinese Medicine Research Project (Funding Reference Number GZKZ-2021-7).

语种：英文

外文关键词：Pulmonary artery aneurysm; Dissection; Pulmonary hypertension; Echocardiography; CTA; Rare case

摘要：Pulmonary artery aneurysm (PAA) and dissection are rare and fatal cardiovascular diseases, characterized by insidious clinical manifestations and posing significant challenges in diagnosis and management. This article reports a case of a patient with PAA complicated by dissection, who died within hours of diagnosis. The patient presented with sudden chest pain and dyspnea, which could easily be misdiagnosed as common emergencies such as acute coronary syndrome. Clinicians should maintain a high index of suspicion when managing high-risk populations. CT pulmonary angiography plays a critical role in confirming the diagnosis. This case underscores the importance of multidisciplinary collaboration and timely initiation of cardiac surgical intervention to improve outcomes. Although the generalizability of the conclusions is limited by the small number of cases, this study provides direction for exploring early biomarkers and optimizing diagnostic and treatment strategies. It also offers a theoretical basis for monitoring and intervening in high-risk populations, which may help reduce the mortality rate of such diseases.