文献类型：期刊文献

中文题名：基于CT影像的骨质疏松性胸腰椎压缩骨折PKP术后三维有限元力学模型的建立与验证

英文题名：CT image-based establishment and verification of three-dimensional finite element biomechanical model for osteoporotic thoracolumbar compression fracture after percutaneous kyphoplasty

作者：权祯[1];张晓刚[1,2];秦大平[1,2];宋敏[1,2];张华[2];张宏伟[2];赵希云[2];王志鹏[2];马涛[1];陈钵[1]

第一作者：权祯

机构：[1]甘肃中医药大学中医临床学院,甘肃兰州730000;[2]甘肃中医药大学附属医院脊柱外科,甘肃兰州730020

第一机构：甘肃中医药大学中医临床学院

年份：2021

卷号：38

期号：3

起止页码：360

中文期刊名：中国医学物理学杂志

外文期刊名：Chinese Journal of Medical Physics

收录：CSTPCD;;CSCD:【CSCD_E2021_2022】；

基金：国家自然科学基金(81760873);甘肃省高等学校创新基金(2020A-073);甘肃中医药大学附属医院青年创新基金(gzfy-2018-11)。

语种：中文

中文关键词：骨质疏松性胸腰椎压缩骨折;三维有限元;生物力学模型;建立与验证

外文关键词：osteoporotic thoracolumbar compression fracture;three-dimensional finite element;biomechanical model;establishment and verification

摘要：目的:建立胸腰椎(T11-L2节段)的三维有限元模型,并验证其生物力学分析有效性。方法:筛选1名T12椎体骨质疏松性压缩骨折的志愿者为建模对象,利用64排螺旋CT进行连续性扫描,扫描区域为脊柱胸腰段T11-L2节段。将CT数据读盘为DICOM格式,导入Mimics 19.0软件进行原始模型的提取与转化;Geomagic Warp 2017软件进行特征去除、光顺、曲面实体拟合;Solidworks 2017软件进行零件结构的组装与附属结构生成;Ansys Workbench 17.0软件添加材料属性、边界条件、坐标及载荷设定及生物力学分析。结果:成功建立了T12椎体压缩骨折T11-L2节段的经皮椎体后凸成形术(PKP)术后三维有限元模型,并测得其前屈、后伸、左侧弯、右侧弯、左旋转、右旋转时的角位移分别为8.3°、3.8°、7.8°、7.6°、3.7°、4.0°,与以往力学实验验证结果位移趋势一致。结论:基于有限元建模软件能成功建立骨质疏松性椎体压缩骨折PKP术后有限元数字模型,有效性验证合格,所建模型可靠,具备生物力学测试性能。
Objective To establish a three-dimensional finite element model of thoracolumbar spine(T11-L2)and to verify its validity in biomechanical analysis.Methods A volunteer with osteoporotic compression fracture of T12 vertebral body was selected as the modeling object,and 64-slice spiral CT was used for continuous scan,with the thoracolumbar spine T11-L2 as the scanning area.The CT data in DICOM format were imported into Mimics 19.0 software for extracting and transforming the original model.Moreover,Geomagic Warp 2017 software was used for feature removal,smoothing,curved surface entity fitting;Solidworks 2017 software for parts assembly and subsidiary structure generation;and Ansys Workbench 17.0 software for the additions of material properties and boundary conditions,coordinate and load setting,and biomechanical analysis.Results A three-dimensional finite element model of the compression fracture segment(T11-L2)of T12 vertebral body was successfully established,and the angular displacements of the anterior flexion,posterior extension,left flexion,right flexion,left rotation and right rotation were measured as 8.3°,3.8°,7.8°,7.6°,3.7°and 4.0°,respectively,which were consistent with the displacement trend verified by previous mechanical experiments.Conclusion The finite element digital model of osteoporotic vertebral compression fracture after percutaneous kyphoplasty can be successfully established based on the finite element modeling software.The established model is proved to be qualified in validity verification and reliable,with biomechanical performances.