文献类型：期刊文献

英文题名：Mediastinal desmoplastic small round cell tumor

作者：Jin, Dacheng[1];Chen, Meng[1];Wang, Bing[1,2];Gou, Yunjiu[1]

第一作者：Jin, Dacheng

通信作者：Gou, YJ[1]

机构：[1]Gansu Prov Hosp, Dept Thoracic Surg 1, Lanzhou, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Dept Clin Med, Lanzhou, Peoples R China

第一机构：Gansu Prov Hosp, Dept Thoracic Surg 1, Lanzhou, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Lanzhou 730000, Peoples R China.

年份：2020

卷号：99

期号：44

起止页码：e22921

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85094935550);WOS:【SCI-EXPANDED(收录号:WOS:000588186500058)】；

语种：英文

外文关键词：chemotherapy; desmoplastic small round cell tumor; mediastinum

摘要：Rationale: Desmoplastic small round cell tumor (DSRCT) is a rare distinct tumor with a high-grade malignancy. Patient concerns: A 51-year-old male visited a local hospital in April 2016 complaining of shortness of breath, chest tightness and pain, and exhibited significant swelling in both sides of the chest. Diagnoses: CT demonstrated thoracic symmetry and no abnormalities were observed in the soft tissues of the ribs and the chest wall. A general observation of CT-guided puncture biopsy revealed 2 stripes of gray and grayish-white puncture tissues of 0.5 and 1 cm in length, respectively, and 0.1 cm in diameter. These results preliminarily suggested a (mediastinum) malignant small round cell tumor. Intervention: Given the progression of the disease, the chemotherapy regimen, consisting of ifosfamide and etoposide, was altered during the course and radiotherapy (total of 70 Gy of mediastinal Y field radiation) was conducted. Outcomes: The patient and his family declined further treatment. Through follow-up, the total survival period was determined as 17 months. Lessons: DSRCT is a rare interstitial malignant tumor. Effective cytoreduction combined with comprehensive therapies could achieve partial remission or prolong the survival of patients.