文献类型：期刊文献

英文题名：The Genus Patrinia: A Review of Traditional Uses, Phytochemical and Pharmacological Studies

作者：He X.; Luan F.; Zhao Z.; Ning N.; Li M.; Jin L.; Chang Y.; Zhang Q.; Wu N.; Huang L.

机构：[1]Honghui Hospital, Xi'An Jiaotong University College of Medicine, 3 Nanguo Road, Xi'an, 710054, China;[2]Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi'an, 710069, China;[3]Department of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, 730000, China;[4]Department of Pharmacy, Xi'An Weiyang District Hospital of Traditional Chinese Medicine, Xi'an, 710016, China;[5]Department of Pharmacy, Lanzhou General Hospital of PLA, Key Laboratory of the Prevention and Treatment for Injury in Plateau of PLA, Lanzhou, 730050, China

第一机构：Honghui Hospital, Xi'An Jiaotong University College of Medicine, 3 Nanguo Road, Xi'an, 710054, China

年份：2017

卷号：45

期号：4

起止页码：637

外文期刊名：American Journal of Chinese Medicine

收录：Scopus(收录号：2-s2.0-85020405058)

语种：英文

外文关键词：Anti-inflammatory; Antitumor; Genus Patrinia; Pharmacology; Phytochemistry; Review; Traditional Uses

摘要：The aim of the present review is to comprehensively outline the botanical description, traditional uses, phytochemistry, pharmacology and toxicology of Patrinia, and to discuss possible trends for the further study of medicinal plants from the genus Patrinia. The genus Patrinia plays an important role in Asian medicine for the treatment of erysipelas, conjunctival congestion with swelling and pain, peri-Appendicular abscesses, lung carbuncle, dysentery, leucorrhea, and postpartum disease. More than 210 chemical constituents have been isolated and identified from Patrinia plants, especially P. scabiosaefolia Fisch., P. scabra Bunge, P. villosa Juss., P. heterophylla Bunge and P. rupestris(Pall.) Juss. Of these compounds, triterpenoids and saponins, iridoids, flavonoids, and lignans are the major or active constituents. Both in vitro and in vivo studies have indicated that some monomer compounds and crude extracts from the genus Patrinia possess wide pharmacological activities, including antitumor, anti-inflammatory, antibacterial, and antiviral effects. In addition, they have been shown to have valuable and positive effects on the immune and nervous system in experimental animals. There are also some reports on the clinical uses and toxicity of these species. However, few reports have been published concerning the material identification or quality control of Patrinia species, and the clinical uses and toxic effects of these plants are relatively sparse. More attention must be given to these issues. ? 2017 World Scientific Publishing Company.