文献类型：期刊文献

中文题名：活血化瘀中药联合米非司酮预防子宫肌瘤剔除术后复发疗效的Meta分析

英文题名：A Meta-analysis of the efficacy of Chinese materia medica for activating blood and resolving stasis plus mifepristone in preventing recurrence after hysteromyomectomy

作者：章宪慧[1];王新斌[1];王丽丽[1];张怡[1];王蓉[1]

第一作者：章宪慧

机构：[1]甘肃中医药大学中西医结合学院,甘肃兰州730000

第一机构：甘肃中医药大学中西医结合学院

年份：2023

卷号：15

期号：2

起止页码：31

中文期刊名：中医临床研究

外文期刊名：Clinical Journal Of Chinese Medicine

基金：甘肃省自然科学基金重点项目(1610RJ2A067);甘肃省高等学校创新基金项目(2121A-077)。

语种：中文

中文关键词：活血化瘀;米非司酮;子宫肌瘤;复发;血清性激素

外文关键词：Activating blood and resolving stasis;Mifepristone;Uterine fibroids;Recurrence;Serum sex hormone

摘要：目的:利用Meta分析活血化瘀中药联合米非司酮预防子宫肌瘤剔除术后复发的有效性。方法:检索中国知网、万方数据库、中国生物医学文献服务系统、PubMed、Web of Science数据库中有关活血化瘀中药联合米非司酮预防子宫肌瘤剔除术后复发的临床随机对照试验,检索时间自建库至2022年3月,运用RevMan 5.3进行Meta分析。结果:纳入临床随机对照试验8项,改良的Jadad评分为2~4分,试验组予活血化瘀中药联合米非司酮治疗,对照组单用米非司酮治疗,试验组降低子宫肌瘤剔除术后复发率及术后血清雌二醇、卵泡刺激素、黄体生成素水平的疗效优于对照组,差异有统计学意义(P<0.05)。结论:活血化瘀中药联合米非司酮能有效调控子宫肌瘤剔除术后性激素水平,降低术后复发率。
Objective:To analyze the efficacy of Chinese materia medica for activating blood and resolving stasis plus mifepristone in preventing recurrence after myomectomy by Meta-analysis.Methods:RCTs of the prevention of recurrence after hysteromyomectomy with Chinese materia medica for activating blood and resolving stasis plus mifepristone were searched from CNKI,Wanfang,CBM,PubMed and other databases.The search time was from inception to March 2022.Meta-analysis were conducted by RevMan 5.3.Results:Eight RCTs were included,and the improved Jadad score was 2~4 points.The test group was treated with Chinese materia medica for activating blood and resolving stasis plus mifepristone,while the control group was treated with mifepristone alone.The efficacy in the test group in reducing the recurrence after myomectomy,and the levels of stradiol,FSH and LH after myomectomy was better than the control group,and the difference was statistically significant(P<0.05).Conclusion:Chinese materia medica for activating blood and resolving stasis plus mifepristone can effectively regulate the level of sex hormone after hysteromyomectomy and reduce the recurrence rate.