文献类型：期刊文献

英文题名：Fully Triazine-Based Covalent Framework for Antibacterial Phototreatment with High Biosafety

作者：Liu, Hu[1,2];Miao, Ruoyan[1];Zhao, Xiaoying[1];Du, Xiaolong[3];Liu, Lizhen[4];Li, Wenfeng[2];Ma, Zhenhui[5];Zhang, Liang[1];He, Jianzheng[6];Xu, Zhichuan J.[4,7]

第一作者：Liu, Hu

通信作者：Liu, H[1];Zhang, L[1];Liu, H[2];Xu, ZJ[3];He, JZ[4];Xu, ZJ[5]

机构：[1]Xian Univ Architecture & Technol, Sch Chem & Chem Engn, Xian 710055, Peoples R China;[2]Chinese Acad Sci, Qinghai Inst Salt Lakes, Qinghai Engn & Technol Res Ctr Comprehens Utilizat, Key Lab Green & Highend Utilizat Salt Lake Resourc, Xining 810008, Peoples R China;[3]Nanjing Univ, Med Sch, Affiliated Hosp, Dept Vasc Surg,Nanjing Drum Tower Hosp, Nanjing 210008, Peoples R China;[4]Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore;[5]Beijing Technol & Business Univ, Dept Phys, Beijing 100048, Peoples R China;[6]Gansu Univ Chinese Med, Coll & Univ, Lanzhou 730000, Peoples R China;[7]Nanyang Technol Univ, Ctr Adv Catalysis Sci & Technol, Singapore 639798, Singapore

第一机构：Xian Univ Architecture & Technol, Sch Chem & Chem Engn, Xian 710055, Peoples R China

通信机构：[1]corresponding author), Xian Univ Architecture & Technol, Sch Chem & Chem Engn, Xian 710055, Peoples R China;[2]corresponding author), Chinese Acad Sci, Qinghai Inst Salt Lakes, Qinghai Engn & Technol Res Ctr Comprehens Utilizat, Key Lab Green & Highend Utilizat Salt Lake Resourc, Xining 810008, Peoples R China;[3]corresponding author), Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore;[4]corresponding author), Gansu Univ Chinese Med, Coll & Univ, Lanzhou 730000, Peoples R China;[5]corresponding author), Nanyang Technol Univ, Ctr Adv Catalysis Sci & Technol, Singapore 639798, Singapore.|[10735]甘肃中医药大学;

年份：2025

卷号：17

期号：34

起止页码：48184

外文期刊名：ACS APPLIED MATERIALS & INTERFACES

收录：;EI(收录号：20253619092103);Scopus(收录号：2-s2.0-105014460975);WOS:【SCI-EXPANDED(收录号:WOS:001553148800001)】；

基金：This study was financially supported by the National Natural Science Foundation of China (Grant Nos. 52271189 and 42477035), the Natural Science Foundation of Qinghai Province for Distinguished Young Scholars (Grant No. 2025-ZJ-966J), and the talent youth project of Chinese Academy of Sciences (Grant No. E410GC03).

语种：英文

外文关键词：covalent triazine framework; phototreatment; full spectral absorption; antibacterialmechanism; biosafety

摘要：The application of antibacterial photocatalytic therapy remains a great challenge due to the limitations of photocatalytic efficiency and biosafety of photocatalysts. Herein, we report an organic semiconductor catalyst featuring a unique covalent triazine framework (CTF) structure, which is entirely composed of triazine-based rings. This catalyst exhibits the lowest forbidden bandgap, full spectral absorption range, and high biosafety, achieving a record-high antibacterial activity under visible light irradiation. The experimental and theoretical results confirm that the CTF structure broadens the light absorption range of carbon nitride and enhances the separation efficiency of photogenerated electron-hole pairs, which improves the photocatalytic activity. The unique CTF structure not only exhibits excellent antibacterial activity toward both Escherichia coli and Staphylococcus aureus but also eradicates Staphylococcus aureus in a mouse wound infection model and greatly promotes wound healing. The in vivo toxicity evaluation was conducted on the physiological activities of Drosophila, confirming the high biosafety and great potential of as-prepared CTF/poly(vinyl alcohol) hydrogel for antibacterial and wound healing applications.