文献类型：期刊文献

中文题名：基于纹党参鲜药材的产地加工炮制一体化技术研究

英文题名：Study on Producing and Preparing Integration Process based on Fresh Codonopsis pilosula Nannf.var.modesta(Nannf.) L.T.Shen

作者：强思思[1,2];高霞[1];马玉玲[1];郑晓萍[1];胡芳弟[1,3];李应东[3]

第一作者：强思思

机构：[1]兰州大学药学院;[2]北京中医药大学第三附属医院;[3]甘肃中医药大学

第一机构：兰州大学药学院

年份：2017

卷号：24

期号：1

起止页码：71

中文期刊名：中国中医药信息杂志

外文期刊名：Chinese Journal of Information on Traditional Chinese Medicine

收录：CSTPCD;;CSCD:【CSCD_E2017_2018】；

基金：甘肃省科技支撑计划-社会发展类(1504FKCA010);甘肃中医药管理局科研课题(GZK-2014-13;GZK-2015-19);兰州市科技计划项目(2013-4-75;2014-2-30)

语种：中文

中文关键词：鲜纹党参;产地加工;炮制;一体化

外文关键词：fresh Wen Codonopsis pilosula; processing in producing areas; preparing; integration

摘要：目的研究不同干燥过程对纹党参饮片有效成分的影响,确定最佳的基于纹党参鲜药材的产地初加工与炮制一体化工艺。方法对采收期的纹党参鲜药材分别采用3种加工炮制方法:1烘箱80℃烘至含水量为药材原始含水量不同百分比(30%~100%)时,分别取出切片,50℃烘干,制得8个饮片样品(XⅠYP1~8)。2鲜纹党参直接在不同温度(50~120℃)分别烘至含水量为药材原始含水量的50%时,取出切片,50℃烘干,制得8个饮片样品(XⅡYP1~8)。3纹党参干药材,闷润,切片,自然晾干,制得传统饮片。采用HPLC测定各样品中党参炔苷和苍术内酯Ⅲ,苯酚-硫酸法和比色法分别测定多糖及总黄酮含量,并同时测定醇浸出物、水浸出物含量。结果饮片XⅠYP3的醇浸出物(55.36%)、水浸出物(54.91%)和苍术内酯Ⅲ(10.95μg/g)含量均高于其他饮片。结论优选的工艺为:80℃烘至含水量50%,切片,干燥。获得的一体化加工工艺较传统方法省时、省力。制得的饮片活性成分含量高。
Objective To study the effects of different drying processes on the effective constituents in Wen Codonopsis pilosula (WPP) Decoction Pieces; To develop the optimized producing and preparing integration process based on fresh WPP. Methods Fresh WPP in harvest period was prepared respectively as follows: ① Fresh WPP was dried to different percentage (30%–100%) of original moisture contents of crude drugs at 80 ℃ in oven, then sliced and dried at 50 ℃ to obtain eight decoction pieces of WPP (XⅠYP1–8). ② The fresh WPP was baked to 50% of water content of crude drug under different temperatures (50–120 ℃), respectively, then sliced and dried at 50 ℃ to obtain eight decoction pieces of WPP (XⅡYP1–8). ③ Dried WPP was moistened, sliced and naturally dried,then were renamed as traditional decoction pieces. The contents of lobetyolin and atractylenolide Ⅲ was determined by HPLC. The phenol-sulfuric acid and colorimetric method were applied respectively to detect contents of polysaccharide and total flavonoids. The contents of aqueous and alcoholic extracts were determined simultaneously.Results The contents of alcoholic extracts (55.36%), aqueous extracts (54.91%) and atractylenolide Ⅲ (10.95 μg/g)in XⅠYP3 pieces were higher than other decoction pieces. Conclusion The optimized process was that fresh WPP was baked to water content of 50% at 80 ℃, then sliced and dried. Compared with conventional preparing methods, the integration process was time-saving and effort-saving. Meanwhile, the prepared pieces have higher content of active ingredients.