文献类型：期刊文献

英文题名：A highly sensitive, single selective, fluorescent sensor for Al³⁺ detection and its application in living cell imaging

作者：Ye, Xing-Pei[1];Sun, Shao-bo[2];Li, Ying-dong[2];Zhi, Li-hua[1];Wu, Wei-na[1];Wang, Yuan[1]

第一作者：Ye, Xing-Pei

通信作者：Wu, WN[1]

机构：[1]Henan Polytech Univ, Dept Chem & Phys, Jiaozuo 454000, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Inst Integrated Tradit & Western Med, Lanzhou 730000, Peoples R China

第一机构：Henan Polytech Univ, Dept Chem & Phys, Jiaozuo 454000, Peoples R China

通信机构：[1]corresponding author), Henan Polytech Univ, Dept Chem & Phys, Jiaozuo 454000, Peoples R China.

年份：2014

卷号：155

起止页码：180

外文期刊名：JOURNAL OF LUMINESCENCE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000341466300028)】；

基金：This work was supported by the National Science Foundation of China (21001040).

语种：英文

外文关键词：Fluorescent sensor; Al3+ ion; Schiff base; Cell imaging; Off-on sensor; Fluorescent probe

摘要：A new o-aminophenol-based fluorogenic chemosensor methyl 3,5-bis((E)-(2-hydroxyphenylimino)methyl)-4-hydroxybenzoate I have been synthesized by Schiff base condensation of methyl 3,5-diformy1-4-hydroxybenzoate with o-aminophenol, which exhibits high selectivity and sensitivity toward Al3+. Fluorescence titration studies of receptors I with different metal cations in CH3OH medium showed highly selective and sensitive towards Al3+ ions even in the presence of other commonly coexisting metal ions. The detection limit of Al3+ ions is at the parts per billion level. Interestingly, the Al(III) complex of 1 offered a large Stokes shift ( >120 nm), which can miximize the selfquenching effect. In addition, possible utilization of this receptor as bio-imaging fluorescent probe to detect Al3+ in human cervical HeLa cancer cell lines was also investigated by confocal fluorescence microscopy. (C) 2014 Elsevier B.V. All rights reserved.