文献类型：期刊文献

中文题名：利胆和胃方联合常规西药治疗肝胃郁热型胃食管反流病40例临床观察

英文题名：Clinical observation on 40 cases of gastroesophageal reflux disease with liver-stomach stagnated heat type treated by Lidan Hewei Fang(利胆和胃方) combined with routine Western medicine

作者：刘俊宏[1];苏海燕[1];汪龙德[1];王淼蕾[2];毛兰芳[1]

第一作者：刘俊宏

机构：[1]甘肃中医药大学附属医院脾胃病科,甘肃兰州730020;[2]甘肃中医药大学中西医结合学院,甘肃兰州730000

第一机构：甘肃中医药大学第二附属医院

年份：2019

卷号：36

期号：4

起止页码：52

中文期刊名：甘肃中医药大学学报

外文期刊名：Journal of Gansu University of Chinese Medicine

基金：2016年国家自然科学基金地区基金项目(81660773);2018年甘肃省中医药管理局项目(GZK-2018-15)

语种：中文

中文关键词：胃食管反流病;肝胃郁热型;利胆和胃方;中西医结合;临床症状积分;临床疗效

外文关键词：gastroesophageal reflux disease;liver-stomach stagnated heat type;Lidan Hewei Fang(利胆和胃方);combined traditional Chinese and Western medicine;clinical symptom score;clinical efficacy

摘要：目的观察利胆和胃方联合常规西药治疗肝胃郁热型胃食管反流病的临床疗效。方法将80例肝胃郁热型胃食管反流病患者采用随机数字表法分为对照组和治疗组,各40例。对照组给予艾司奥美拉唑镁肠溶片、枸橼酸莫沙必利分散片口服,治疗组在对照组治疗方法的基础上给予利胆和胃方口服,治疗1个月后比较2组的临床疗效及治疗前后的临床症状积分。结果对照组总有效率为82.5%,治疗组为95.0%,2组比较差异有统计学意义(P<0.05);治疗后2组各项临床症状积分及总积分均明显降低,与同组治疗前比较差异有统计学意义(P<0.05),且治疗组降低更明显,与对照组治疗后比较差异均有统计学意义(P<0.05)。结论利胆和胃方联合常规西药治疗肝胃郁热型胃食管反流病可明显改善患者的临床症状,疗效确切,值得临床推广应用。
Objective To observe the clinical efficacy of Lidan Hewei Fang(利胆和胃方)combined with routine Western medicine in the treatment of gastroesophageal reflux disease with liver-stomach stagnated heat type.Methods Eighty cases of gastroesophageal reflux disease with liver-stomach stagnated heat type were divided into control group and treatment group according to random number table method,with 40 cases in each.The control group was given esomeprazole magnesium enteric-coated tablets and mosapride citrate dispersible tablets orally,on this basis,the treatment group was given Lidan Hewei Fang orally.After treatment for 1 month,the clinical efficacy and clinical symptom score before and after treatment of the 2 groups were compared.Results The total effective rate of the control group was 82.5%,that of the treatment group was 95.0%,and the difference between the 2 groups was statistically significant(P<0.05).After treatment,various clinical symptom score and the total score of the 2 groups all significantly decreased,and the difference was statistically significant compared with the same group before treatment(P<0.05),moreover,the treatment group decreased more significantly,and the difference was statistically significant compared with the control group after treatment(P<0.05).Conclusion It can markedly improve the clinical symptoms of the patients with definite curative effects to use Lidan Hewei Fang combined with routine Western medicine in the treatment of gastroesophageal reflux disease with liver-stomach stagnated heat type,which deserves clinical promotion and application.