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艾灸对类风湿性关节炎滑膜细胞炎性损伤修复机制的现代研究进展     被引量:13

Research review on repair mechanism of moxa-wool moxibustion for inflammatory damage of rheumatoid arthritis synovial cells

文献类型:期刊文献

中文题名:艾灸对类风湿性关节炎滑膜细胞炎性损伤修复机制的现代研究进展

英文题名:Research review on repair mechanism of moxa-wool moxibustion for inflammatory damage of rheumatoid arthritis synovial cells

作者:朱田田[1];赵中亭[1];赵怡坤[1];严兴科[1]

第一作者:朱田田

机构:[1]甘肃中医药大学,兰州730000

第一机构:甘肃中医药大学

年份:2017

卷号:32

期号:6

起止页码:2599

中文期刊名:中华中医药杂志

外文期刊名:China Journal of Traditional Chinese Medicine and Pharmacy

收录:CSTPCD;;北大核心:【北大核心2014】;CSCD:【CSCD2017_2018】;

基金:国家自然科学基金项目(No.81560791)~~

语种:中文

中文关键词:类风湿性关节炎;滑膜细胞;艾灸;综述;炎性损伤;修复机制

外文关键词:Rheumatoid arthritis;;Synovial cells;;Moxa-wool moxibustion;;Review;;Inflammatory damage;;Repair mechanism

摘要:滑膜细胞的炎性损伤是类风湿性关节炎(RA)发病的核心病理过程。艾灸治疗RA疗效确切,且大量实验研究也证实了艾灸对RA滑膜细胞因炎性损伤所导致的结构和功能异常具有良好的修复作用。笔者检索了近10年的实验研究文献,从滑膜细胞的形态结构、凋亡、增殖进程、分泌功能、血管翳形成及炎性细胞通路等方面总结了艾灸对RA滑膜细胞炎性损伤的修复机制,为今后的研究提供参考和依据。
The inflammatory injury of synovial cell is the core pathologic processes of rheumatoid arthritis(RA). Clinical application of moxa-wool moxibustion in the treatment of RA has significant clinical effect, and a large numbers of experimental studies have shown that moxa-wool moxibustion has a good regulating effect on abnormal structure and function of RA synovial cell that caused by inflammatory injury. The repairing mechanism of moxa-wool moxibustion for abnormalities of RA synovial cell was summarized based on 10 years of literature researches from the aspects of morphology, apoptosis and proliferation process, secretion, pannus formation and inflammatory pathways, so as to provide reference and basis for further research.

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