文献类型：期刊文献

英文题名：Integrative transcriptome and metabolome revealed the molecular mechanism of Bacillus megaterium BT22-mediated growth promotion in Arabidopsis thaliana

作者：Liu, Xiao[1,2];Du, Yan[1,2];Na, Xiaofan[3];Wang, Man[4];Qu, Ying[1,2,7];Ge, Linghui[5];Wang, Yuanmeng[5];Gao, Linqi[6];Bai, Wenke[6];Bi, Yurong[3];Zhou, Libin[1,2,7]

第一作者：Liu, Xiao

通信作者：Zhou, LB[1]

机构：[1]Chinese Acad Sci, Inst Modern Phys, Biomed Ctr, Biophys Grp, Lanzhou 730000, Peoples R China;[2]Univ Chinese Acad Sci, Beijing 100049, Peoples R China;[3]Lanzhou Univ, Coll Life Sci, Lanzhou 730000, Peoples R China;[4]Lanzhou Univ Technol, Coll Life Sci & Engn, Lanzhou 730050, Peoples R China;[5]Gansu Univ Chinese Med, Coll Pharm, Lanzhou 730000, Peoples R China;[6]Lueyang Cty Jinxiu Agr Dev Co Ltd, Lueyang 724300, Hanzhong, Peoples R China;[7]Kejin Innovat Inst Heavy Ion Beam Biol Ind, Baiyin 730900, Peoples R China

第一机构：Chinese Acad Sci, Inst Modern Phys, Biomed Ctr, Biophys Grp, Lanzhou 730000, Peoples R China

通信机构：[1]corresponding author), Chinese Acad Sci, Inst Modern Phys, Biomed Ctr, Biophys Grp, Lanzhou 730000, Peoples R China.

年份：2023

卷号：285

外文期刊名：JOURNAL OF PLANT PHYSIOLOGY

收录：;Scopus(收录号：2-s2.0-85156200812);WOS:【SCI-EXPANDED(收录号:WOS:001012849200001)】；

基金：This work was supported by grants from Crop Varietal Improvement and Insect Pests Control by Nuclear Radiation; Youth Innovation Promotion Association of CAS (Y201974); Ecological Planting and Quality Assurance Project of Daodi Medicinal Materials (China Science and Technology for Traditional Chinese Medicine (2020) 153).

语种：英文

外文关键词：Plant growth -promoting rhizobacteria (PGPR); Bacillus megaterium; Arabidopsis thaliana; Transcriptome; Metabolome

摘要：Plant growth-promoting rhizobacteria (PGPR) can promote plant growth and protect plants from pathogens, which contributes to sustainable agricultural development. Several studies have reported their beneficial characteristics in facilitating plant growth and development and enhancing plant stress resistance through different mechanisms. However, there is still a challenge to study the molecular mechanism of plant response to PGPR. We integrated the transcriptome and metabolome of Arabidopsis thaliana (Arabidopsis) to understand its responses to the inoculation with an isolated PGPR strain (BT22) of Bacillus megaterium. Fresh shoot weight, dry shoot weight and leaf number of Arabidopsis were increased by BT22 treatment, showing a positive growth-promoting effect. According multi-omics analysis, 878 differentially expressed genes (296 up-regulated, 582 down-regulated) and 139 differentially expressed metabolites (66 up-regulated, 73 down-regulated) response to BT22 inoculation. GO enrichment results indicate that the up-regulated genes mainly enriched in the regulation of growth and auxin response pathways. In contrast, the down-regulated genes mainly enriched in wounding response, jasmonic acid and ethylene pathways. BT22 inoculation regulated plant hormone signal transduction of Arabidopsis, including auxin and cytokinin response genes AUX/IAA, SAUR, and A-ARR related to cell enlargement and cell division. The contents of nine flavonoids and seven phenylpropanoid metabolites were increased, which help to induce systemic resistance in plants. These results suggest that BT22 promoted Arabidopsis growth by regulating plant hormone homeostasis and inducing metabolome reprogramming.