文献类型：期刊文献

中文题名：甘草苷的提取纯化和药理作用研究进展

英文题名：Extraction and Purification of Glycyrrhizin and Its Pharmacological Effects:A Review

作者：杨倩倩[1];孟子盈[1];王晓禹[1];房敏[1];吴国泰[1,2]

第一作者：杨倩倩

机构：[1]甘肃中医药大学药学院,甘肃兰州730000;[2]甘肃省中药药理与毒理学重点实验室,甘肃兰州730000

第一机构：甘肃中医药大学药学院（西北中藏药协同创新中心办公室）

年份：2023

卷号：42

期号：4

起止页码：12

中文期刊名：中国野生植物资源

外文期刊名：Chinese Wild Plant Resources

收录：CSCD:【CSCD_E2023_2024】；

基金：甘肃省教育厅双一流学科建设重点科研项目(GSSYLXM-05)。

语种：中文

中文关键词：甘草苷;提取纯化;药理作用

外文关键词：Glycyrrhizin;Extraction and Purification;Pharmacological effects

摘要：甘草是我国传统的中药材,含有多种生物活性成分,其中甘草苷是重要的黄酮类化合物,提取分离技术难度较大,总结发现甘草苷常用有机溶剂、加热回流、闪式提取、超声波辅助提取、微波辅助提取、高压脉冲电场法等方法提取,有机溶剂、大孔树脂、无机陶瓷超滤、超滤-络合萃取及反萃取技术进行分离纯化。与此同时,已有研究表明甘草苷具有抗抑郁、抗氧化、抗炎、抗病毒、解毒等药理作用,为进一步研究开发甘草苷提供了参考依据。
Licorice is a traditional Chinese herbal medicine in China,containing a variety of biologically active ingredients,of which glycyrrhizin is an important flavonoid.The extraction and separation techniques are difficult and commonly used for extraction by organic solvents,heating reflux,flash extraction,ultrasonic-assisted extraction,microwave-assisted extraction,high-voltage pulsed electric field method,and separation and purification by organic solvents,macroporous resin,inorganic ceramic ultrafiltration,ultrafiltration-complexion extraction and reverse extraction techniques based on existing research reports.The pharmacological effects of glycyrrhizin,such as antidepressant,antioxidant,anti-inflammatory,antiviral,and detoxification were discovered.The review provided a reference basis for further research and development of glycyrrhizin.