文献类型：期刊文献

英文题名：Biomechanical changes in spinal motion and imaging characteristics following vertebral height restoration via reduction manipulation in patients with osteoporotic vertebral compression fractures

作者：Qin, Da-Ping[1,2];Gao, Guo-Dong[2];Zhang, Xiao-Gang[2];Zhao, Ya-Wen[2];Quan, Zhen[2];Wang, Zhi-Peng[2];Xu, Bin[1];Zhao, Wen-Tao[3];Xu, Shi-Wei[2]

第一作者：秦大平

通信作者：Qin, DP[1]

机构：[1]Gansu Univ Chinese Med, Clin Coll Tradit Chinese Med, Lanzhou 730000, Peoples R China;[2]Gansu Univ Chinese Med, Affiliated Hosp, 732 JiaYuguan West Rd, Lanzhou 730020, Gansu, Peoples R China;[3]Yunnan Univ Chinese Med, Affiliated Hosp 1, 1076 Yuhua Rd, Kunming 650500, Yunnan, Peoples R China

第一机构：甘肃中医药大学中医临床学院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Clin Coll Tradit Chinese Med, Lanzhou 730000, Peoples R China.|[10735ccd4a8840d96ab71]甘肃中医药大学中医临床学院;[10735]甘肃中医药大学;

年份：2026

卷号：45

外文期刊名：INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT

收录：Scopus(收录号：2-s2.0-105049041973);WOS:【ESCI(收录号:WOS:001867519200001)】；

基金：This study was supported by the National Natural Science Founda-tion of China (Grant Nos. 82260941, 81760873) ; Gansu Provincial University Young Doctor Support Program (No. 2023QB-089) ; Gansu Provincial Innovation Fund Project (No. 2026A-107) ; Lanzhou Munic-ipal Talent Innovation and Entrepreneurship Project (No. 2021-RC-101) .

语种：英文

外文关键词：Percutaneous kyphoplasty; Percutaneous vertebroplasty; Osteoporotic vertebral compression fractures; TCM hyperextension manipulation; Spinal biomechan

摘要：Objectives: This study aimed to compare the clinical efficacy of three minimally invasive regimens for patients with osteoporotic vertebral compression fractures (OVCF): percutaneous kyphoplasty (PKP), percutaneous vertebroplasty (PVP), and TCM hyperextension reduction manipulation combined with PVP (TCMHR-PVP). Methods: We retrospectively analyzed clinical data from 150 OVCF patients admitted to our hospital between March 2016 and June 2019. Patients were equally divided into three groups (n = 50 per group): Group A (PKP), Group B (PVP), and Group C (TCMHR-PVP). The Visual Analog Scale (VAS) was used to evaluate low back pain intensity, and thoracolumbar spinal range of motion was recorded at preoperative baseline and follow-up timepoints: 24 h, 30 days, 90 days, 180 days, and 1 year. Observation indicators included sagittal Cobb angle kyphosis correction rate, postoperative refracture risk of fractured and adjacent vertebrae, and long-term spinal biomechanical stability.
Results: No postoperative complications such as deep vein thrombosis and surgical site infection were detected at the 3-month and 6-month follow-ups. All three groups achieved obvious imaging improvement, with Group C showing the optimal effect, followed by Group A and Group B. Intergroup comparison showed statistically significant differences in the sagittal Cobb angle restoration rate of fractured vertebrae among the three groups and between Group B and Group C (both P < 0.05). The VAS pain improvement rate was significantly elevated postoperatively in all groups. Group C obtained superior pain relief and recovery of daily living function compared with Group A (P < 0.05), while no significant difference in VAS was found between preoperative and postoperative data within Group B (P > 0.05). No significant intergroup differences in Oswestry Disability Index (ODI) improvement rates were observed at baseline and early follow-up between Group A and Group C. Significant ODI differences existed among all three groups at the 6-month follow-up (P < 0.05), and differences between Group A and Group C as well as preoperative vs postoperative of Group B remained significant at 1 and 3 months (P < 0.05). Group B had a significantly higher risk of adjacent vertebral refracture (P < 0.05). Oneyear overall comparison showed no intergroup difference in refracture incidence (P > 0.05). Significant disparities were observed among three groups at 1, 3 and 6 months postoperatively (P < 0.05), but disappeared at the 1-year follow-up (P > 0.05).
Conclusions: All three surgical interventions can effectively alleviate back pain, reinforce and stabilize fractured vertebrae, restore vertebral height, and correct thoracolumbar kyphotic deformity. Long-term follow-up found that patients receiving simple PVP suffered persistent residual lumbago, and PKP patients presented recurrent low back pain. Both surgeries are accompanied by postoperative vertebral height loss and elevated refracture risk of fractured and adjacent vertebrae. These adverse outcomes break musculoskeletal biomechanical balance, reduce long-term spinal stability, and eventually accelerate thoracolumbar degenerative changes.