文献类型：期刊文献

英文题名：Case Report: Unicentric Castleman disease at the superior border of the pancreatic body mimicking a pancreatic neuroendocrine tumor: a case report and literature review

作者：Yang, Linru[1,2];Liu, Jin[1];Zhang, Junhua[1,3]

第一作者：Yang, Linru

通信作者：Zhang, JH[1];Zhang, JH[2]

机构：[1]Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[2]Gansu Prov Hosp, Dept Surg Oncol, Lanzhou, Peoples R China;[3]Gansu Univ Chinese Med, Lanzhou Petrochemical Gen Hosp, Affiliated Hosp 4, Dept Crit Care Med, Lanzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Lanzhou Petrochemical Gen Hosp, Affiliated Hosp 4, Dept Crit Care Med, Lanzhou, Peoples R China.|[10735]甘肃中医药大学;

年份：2026

卷号：13

外文期刊名：FRONTIERS IN SURGERY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001884771600001)】；

基金：The author(s) declared that financial support was received for this work and/or its publication. This work was supported by the Graduate Student Innovation and Entrepreneurship Project of Gansu University of Chinese Medicine (Grant No. 2026CXCY-086).

语种：英文

外文关键词：case report; differential diagnosis; laparoscopic excision; pancreatic neuroendocrine tumor; peripancreatic mass; unicentric Castleman disease

摘要：Peripancreatic unicentric Castleman disease is rare and may mimic a primary pancreatic neoplasm because it often presents as a well-circumscribed hypervascular mass. We report a 26-year-old woman with type 2 diabetes mellitus in whom an incidentally detected upper abdominal mass was initially considered to arise from the pancreatic body. Computed tomography and magnetic resonance imaging showed a sharply marginated hypervascular lesion with diffusion restriction at the superior border of the pancreatic body, leading to a preoperative suspicion of pancreatic neuroendocrine tumor. Laparoscopic exploration revealed a well-encapsulated mass in the lesser sac closely abutting the superior surface of the pancreas. A clear dissection plane between the lesion and the pancreatic parenchyma allowed complete excision without pancreatic resection or splenectomy. Histopathological examination confirmed hyaline vascular-type unicentric Castleman disease. The postoperative course was uneventful, and no residual or recurrent lesion was detected during 1 year of follow-up; glycemic status also remained stable. This case highlights that close proximity of a hypervascular mass to the pancreas does not necessarily indicate pancreatic origin. Careful multiplanar imaging and direct intraoperative assessment of the lesion-pancreas interface may help determine the appropriate surgical extent and avoid unnecessary pancreatic resection when complete excision is technically feasible.