详细信息

Compound kushen injection for multiple myeloma A protocol of systematic review and meta-analysis  ( SCI-EXPANDED收录)   被引量:1

文献类型:期刊文献

英文题名:Compound kushen injection for multiple myeloma A protocol of systematic review and meta-analysis

作者:Yang, Xinwei[1];Zhao, Xiyun[2];Wang, Xiaoxia[3]

第一作者:Yang, Xinwei

通信作者:Wang, XX[1]

机构:[1]Gansu Prov Hosp Tradit Chinese Med, Dept Hematol, Lanzhou, Peoples R China;[2]Gansu Univ Tradit Chinese Med, Affiliated Hosp, Lanzhou, Peoples R China;[3]Gansu Gem Flower Hosp, 733 Fuli Rd, Lanzhou, Gansu, Peoples R China

第一机构:Gansu Prov Hosp Tradit Chinese Med, Dept Hematol, Lanzhou, Peoples R China

通信机构:[1]corresponding author), Gansu Gem Flower Hosp, 733 Fuli Rd, Lanzhou, Gansu, Peoples R China.

年份:2019

卷号:98

期号:50

外文期刊名:MEDICINE

收录:;Scopus(收录号:2-s2.0-85076944545);WOS:【SCI-EXPANDED(收录号:WOS:000511433000034)】;

基金:This work is supported by Gansu science and technology department key research and development projects: 18YF1FA043.

语种:英文

外文关键词:compound kushen injection; efficacy; meta-analysis; multiple myeloma; safety

摘要:Background: Compound kushen injection is increasingly used to treat various cancers. However, its role in the management of multiple myeloma (MM) is still controversial and requires further clarification. The aim of this study is to evaluate efficacy and safety of compound kushen injection for MM through systematic review and meta-analysis. Methods: We are going to search the 6 electronic databases: PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Wangfang and Chinese Biomedical Literature Database. General characteristics and Specific trial characteristics will be collected from the included studies. The outcomes included overall response rate, complete response rate, 3-year progression-free survival rate, 3-year overall survival rate, and different types of treatment-related adverse events. We calculated the risk ratios as well as their 95% confidence intervals of these outcomes and pooled the results through RevMan 5.2 software. Discussion: The results of the study will be submitted to a peer-reviewed journal for publication. Ethics and dissemination: This study is not a clinical study, ethical approval is not required.

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