文献类型：期刊文献

英文题名：Clinical observation of efficacy in adhesive intestinal obstruction with Medicine: a randomized controlled trial

作者：Zhang, Xin[1,2,3];Cao, Jia[4,5];Luo, Chengping[1,2,3];Fan, Yibin[4,5];Du, Jie[6,7]

第一作者：张欣;Zhang, Xin

通信作者：Du, J[1];Du, J[2]

机构：[1]Gansu Univ Chinese Med, Lanzhou 730050, Peoples R China;[2]China West Normal Univ, Gaoping Dist Peoples Hosp, Dept Gastrointestinal Surg, Affiliated Hosp, Nanchong 637000, Peoples R China;[3]China West Normal Univ, Affiliated Hosp, Nanchong 637000, Peoples R China;[4]North Sichuan Med Coll, Dept Tradit Chinese Med & Surg, Nanchong Tradit Chinese Med Hosp, Nanchong 637000, Peoples R China;[5]Nanchong Hosp Tradit Chinese Med, Nanchong 637000, Peoples R China;[6]Sichuan Univ, West China Sch Publ Hlth, Dept Urol & Pelv Surg & Androl, Chengdu 610041, Sichuan, Peoples R China;[7]Sichuan Univ, West China Hosp 4, Chengdu 610041, Sichuan, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Sichuan Univ, West China Sch Publ Hlth, Dept Urol & Pelv Surg & Androl, Chengdu 610041, Sichuan, Peoples R China;[2]corresponding author), Sichuan Univ, West China Hosp 4, Chengdu 610041, Sichuan, Peoples R China.

年份：2025

卷号：45

期号：1

起止页码：115

外文期刊名：JOURNAL OF TRADITIONAL CHINESE MEDICINE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001422750400001)】；

基金：Nanchong City Science and Technology Plan Project: the Application of Tongli Shugan Liqi Method in the Treatment of Adhesive Intestinal Obstruction and its Effect on Inflammatory Indicators Interleukin-6, C-reactive protein and Procalcitonin (21YFZJ0108)

语种：英文

外文关键词：intestinal obstruction; interleukins; C-reactive protein; post-abdominal surgery

摘要：OBJECTIVE: To explore the treatment efficacy of integrated Chinese medicine (Chaihu Shugan San,(sic)(sic) (sic)(sic)(sic), CSS) and western therapy in the treatment of adhesive intestinal obstruction (AIO), to provide new ideas for the management of the disease. METHODS: In our single-blind randomized controlled study, 120 patients with AIO who were hospitalized in The Affiliated Hospital of China West Normal University Nan Chong Gaoping District People's Hospital from January 2021 to June 2022 and met the inclusion criteria were categorized into the treatment group and the control group. Patients from the control group were administered basic Western Medicine therapy, whereas patients from the treatment group were administered basic Western Medicine therapy plus CSS by gastric tube injection. Subsequently, the time to first anal exhaustion and defecation, time to relief of abdominal distension and pain, days of hospitalization, Traditional Chinese Medicine (TCM) symptom scores, interleukin-6 (IL-6), C-reactive protein (CRP) and procalcitonin (PCT) levels in the 2 groups were recorded and compared. RESULTS: The comparison of clinical efficacy of the treatment group were better than the control group. The TCM symptom score was considerably lower in the treatment group; the inflammation indicators CRP, IL-6, and PCT also decreased statistically when comparing the control group. Furthermore, there were significantly reduced in the time to first exhaustion, time to first defecation, time to relief of abdominal pain and distension, and days of hospitalization in the treatment group versus the control group. CONCLUSION: CSS could suppress the inflammatory reaction, reduce days of hospitalization, relieve clinical symptoms in AIO patients with reliable efficacy and high safety and is worthy of clinical application.