文献类型：期刊文献

英文题名：Different exercise therapies for treating heart failure A protocol for overview of systematic reviews and network meta-analysis

作者：Zhang, Li[1,2];Zhao, Xiao-Peng[1];Qiao, Li-juan[3];Wei, Wan-xia[1];Wei, Min[1];Ding, Jin[1];Li, Ying-dong[4]

第一作者：Zhang, Li;张丽

通信作者：Li, YD[1];Ding, J[2]

机构：[1]Gansu Univ Chinese Med, Affiliated Hosp, Cardiovasc Clin Med Ctr, Ward 3, Lanzhou, Peoples R China;[2]Lanzhou Univ, Evidence Based Nursing Ctr, Sch Nursing, Lanzhou, Peoples R China;[3]Gansu Prov Matern & Child Care Hosp, Gen Dept Children, Lanzhou, Peoples R China;[4]Gansu Univ Chinese Med, 732 Jiayuguan West Rd, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学第二附属医院

通信机构：[1]corresponding author), Gansu Univ Chinese Med, 732 Jiayuguan West Rd, Lanzhou 730000, Gansu, Peoples R China;[2]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, 732 Jiayuguan West Rd, Lanzhou 730000, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：99

期号：42

起止页码：e22710

外文期刊名：MEDICINE

收录：;Scopus(收录号：2-s2.0-85094222247);WOS:【SCI-EXPANDED(收录号:WOS:000589394700056)】；

基金：This work was funded by Research Center of Traditional Chinese Medicine, Gansu Province (zyzx-2020-36). Traditional Chinese medicine (TCM) evidence-based Capacity Building project, Clinical practice of TCM comprehensive prevention and treatment of heart failure based on evidence-based research (2019 XZZX-XXG002).

语种：英文

外文关键词：exercise therapy; heart failure; meta-analysis; systematic review

摘要：Background: Exercise therapies has been shown to be safe and effective as a non-pharmacological management for treating heart failure, At the same time, many clinical trials, systematic review, and meta-analyses have demonstrated the advantages of exercise therapies in heart failure. However, the methodological quality of these systematic reviews and the differences in efficacy between different exercise modes are unclear. Therefore, this study intends to overview of systematic reviews and network meta-analysis of exercise therapies intervention in heart failure, and finally to rank the effects of exercise therapies in the intervention of heart failure, so as to provide certain reference for clinical decision-making. Methods: From the seven databases: PubMed, EMBASE.com, Web of Science, the Cochrane Library, Chinese biomedical literature database (CBM), Chinese National Knowledge Infrastructure (CNKI), Wan fang Database, and Chongqing VIP (CQVIP) databases. To search for systematic or meta-analysis of different exercise therapies for heart failure from inception to August 2020. According to the inclusion criteria and exclusion criteria, the two researchers independently selected articles and extracted data. In case of differences, a third party shall be sought for settlement. The AMSTAR2 scale, PRISMA scale and GRADE were used to assess the quality and evidence grade of the literature. The eligible randomized controlled trials (RCTs) were selected from the included systematic reviews and updated RCTs from the above systematic reviews to August 2020. GRADE was used for the risk of bias of the included RCTs. Pairwise meta-analyses were performed using the random-effects model, and network meta-analysis of the included RCTs were performed the frequentist framework. All data analyses were completed in Stata 15.0. Results: Finally, a total of 33 articles related to systematic review and meta-analysis were included, there are 28 articles in Chinese and 5 articles in English. The results of this overview and network meta-analysis will be submitted to a peer-reviewed journal for publication. Conclusion: This review will provide a comprehensive overview of existing systematic reviews of exercise therapies interventions for heart failure and provide recommendations for clinical practice or guidelines. Protocol Registration: INPLASY202080118.