文献类型：期刊文献

英文题名：Transcatheter closure of post-myocardial infarction ventricular septal defect: A systematic review and single-arm meta-analysis

作者：Yi, Kang[1,2,3];Liu, Chengfei[4];Xu, Zhi[2,5];Xu, Jianguo[3];Dong, Xin[2,8];Zhang, Xin[2,6];Wang, Wenxin[2,6];Ding, Jianing[7];You, Tao[1,2]

第一作者：Yi, Kang

通信作者：You, T[1]

机构：[1]Gansu Prov Hosp, Dept Cardiovasc Surg, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China;[2]Gansu Int Sci & Technol Cooperat Base Diag & Treat, Lanzhou, Peoples R China;[3]Lanzhou Univ, Evidence Based Med Ctr, Sch Basic Med Sci, Lanzhou, Peoples R China;[4]Lanzhou Univ, Clin Med Coll 1, Lanzhou, Peoples R China;[5]Peoples Hosp Tongwei Cty, Dept Cardiol, Dingxi, Gansu, Peoples R China;[6]Gansu Univ Chinese Med, Sch Clin Med 1, Lanzhou, Peoples R China;[7]Lanzhou Univ, Clin Med Coll 2, Lanzhou, Peoples R China;[8]Gansu Prov Hosp, Dept Ultrasound, Lanzhou, Peoples R China

第一机构：Gansu Prov Hosp, Dept Cardiovasc Surg, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Prov Hosp, Dept Cardiovasc Surg, 204 Donggang West Rd, Lanzhou 730000, Gansu, Peoples R China.

年份：2023

卷号：9

期号：6

外文期刊名：HELIYON

收录：;Scopus(收录号：2-s2.0-85160815505);WOS:【SCI-EXPANDED(收录号:WOS:001019342000001)】；

基金：Acknowledgements The outhors gratefully acknowledge the financial supports by the Natural Science Foundation of Gansu Province under project number 22JR5RA655 and 21JR1RA027.

语种：英文

外文关键词：Transcatheter occlusion technique; Interventional technique; Acute myocardial infarction; Ventricular septal defect; Systematic review; Single -arm meta -analysis

摘要：Background: Ventricular septal defects (VSDs) are one of the mechanical complications of acute myocardial infarction (AMI). Because of the high risks of mortality and postoperative complications, a new alternative method is needed. With the development of interventional medicine, transcatheter closure has been increasingly performed for postmyocardial infarction ventricular septal defects (PMIVSDs). The aim of this study is to explore the feasibility and safety of transcatheter closure of PMIVSDs by meta-analysis.Methods: The included studies were mainly single-arm studies of transcatheter closure of PMIVSDs. We compared VSD size, device size, preoperative risk factors and interventions among PMIVSD patients. We analysed the transcatheter closure success rate, the 30-day mortality rate, and the incidence of residual shunts.Results: A total of 12 single-arm articles (284 patients) were included. The combined incidences of preoperative hypertension, hyperlipidaemia, and diabetes were 66% [95% CI 0.56-0.75], 54% [95% CI 0.40-0.68], and 33% [95% CI] 0.21-0.46], respectively. Multiple studies reported the combined incidences of preoperative PCI, IABP, and CABG, which were 46% [95% CI 0.15-0.80], 60% [95% CI 0.44-0.75], and 8% [95% CI 0.02-0.18]. Eleven studies reported the number of successful closures and the 30-day mortality rate; the success rate was 90% [95% CI 0.86-0.94], and the 30-day mortality rate reached 27% [95% CI 0.86-0.94].Conclusion: For patients with PMIVSD, transcatheter closure in the acute phase can be used as a rescue measure, while in the chronic phase, it is more effective and has a lower mortality rate, but the effect of selection bias should be considered. Residual shunts are a long-term complication that have a high incidence and long-lasting effects on patients. More large, multicentre, randomized controlled trials are needed in the future to confirm the safety and reliability of transcatheter closure of PMIVSDs.