文献类型：期刊文献

中文题名：新型冠状病毒肺炎藏医防治方案的组方配伍规律及药性功效研究

英文题名：Study on Compatibility Rule,Property and Efficacy of Tibetan Medicine to Prevent and Treat Corona Virus Disease 2019

作者：加羊加措[1,2];李先加[2];贡保东知[1];完么才让[3];阿达[1];文成当智[4];卓玛草[1];曾商禹[4]

第一作者：加羊加措

机构：[1]甘肃中医药大学藏医学院,合作747000;[2]青海大学藏医学院,西宁810016;[3]甘肃中医药大学中医临床学院,兰州730000;[4]成都中医药大学民族医药学院,成都611130

第一机构：甘肃中医药大学藏医学院

年份：2020

卷号：36

期号：5

起止页码：33

中文期刊名：中药药理与临床

外文期刊名：Pharmacology and Clinics of Chinese Materia Medica

收录：北大核心:【北大核心2017】；CSCD:【CSCD2019_2020】；

基金：甘肃中医药大学新型冠状病毒感染的肺炎应急防治专项(编号:2020XGZX-11);甘肃省高等学校创新能力提升项目(编号:2020A-076)。

语种：中文

中文关键词：新冠肺炎;藏医;防治;组方配伍;药性功效

外文关键词：COVID-19;Tibetan medicine;Prevention and cure;Compatibility of medicines;Drug Property and Efficacy

摘要：目的:新型冠状病毒肺炎疫情发生以来,我国涉藏地区卫生主管部门制定了一批藏医防治方案,推荐了藏药防治新冠肺炎方剂,本文有效总结各方案方剂的组方配伍规律和药性功效。方法:本研究以全国涉藏地区州级及以上卫生管理部门发布的8套藏医防治方案为依据,采用数据挖掘和可视化方法,以方剂-药物-药性-(六味、三化味、十七效)-药效(二十种特性)的思路,研究新冠肺炎藏药方组方配伍规律和药性功效。结果:各方案中有总60首藏药方剂,其中频次最高的为催汤丸、流感丸、九味防瘟散等;单味频次最高的为诃子、藏木香等;药对出现频次最高的为诃子-藏木香;药性聚类发现达斯玛保丸偏凉性,常松八味沉香丸偏温性,整体上凉性方剂占主导;六味和三化味中苦味和苦化味居多;十七效中燥效、糙效、动效居多。从用药可以看出其病机主要为隆热上亢、培根偏生、粘柔增生所致。藏医防治新冠肺炎组方配伍主要以“热症催熟与祛邪”相结合的思路,其药性功效模式主要为“苦味-苦化味-糙、动、轻、燥”。主要对治培根粘性、柔性、稳性、腻性。结论:本研究初步总结和探索了藏医防治新冠肺炎组方配伍的共性,旨在为加强临床精准施治、提高藏医救治效果、推进藏药防控资源管理提供多方面参考。
Objective:Since the outbreak of COVID-19,Health authorities in Tibet related areas have formulated a number of Tibetan medicine prevention and control programs.They also recommended Tibetan medicine Prescriptions for COVID-19.In this study,we analyzed the compatibility rule,the property and efficacy of the prescriptions.Methods:8 Tibetan medicine prevention and control programs issued by the Health management departments above the state level in Tibet related areas were selected.Based on data mining and visualization methods,with the idea of prescription-drug-property(6 flavors,3 hua flavors,17 effects)-efficacy(20 characteristics),the compatibility rule,the property and efficacy of the descriptions were analyzed.Results:60 Tibetan prescriptions in one control program were studied,the prescriptions with highest use frequency were Cuitang pill,Liugan pill,Jiuwei Fangwen San,etc.Single drugs with the highest use frequency were myrobalan,Tibet inula root,etc.Drug pair with the highest use frequency was myrobalan-Tibet inula root.Cluster analysis showed that Dasimabao pill had Liang property,Changsong Baweichenxiang pill had Wen property,and the prescriptions of Liang property played the important role.In 6 flavors and 3 Hua flavors analysis,Ku and Ku Hua flavors played the main role.In 17 effects analysis,Zao,Cao and Dong were the main effects.The pathogenesis of the disease was mainly Longreshangkang,Peigenpiansheng,Nianrouzengsheng.The compatibility rule of Tibetan medicine in the treatment of COVID-19 was based on the theory of“Rezhengcuishu and Quxie”,while its property and effects were mainly“Ku flavor-Ku Huaflavor-Cao,Dong,Qing,Zao”,they treated“Nian,Rou,Wen and Ni”of Peigen.Conclusion:This study preliminarily summarized and explored the commonalities of Tibetan medicine to prevent and cure COVID-19,in order to provide references for strengthening the clinical precise treatment,improving the treatment efficacy of Tibetan medicine,and promoting the resource management of Tibetan medicine prevention and control.