文献类型：期刊文献

英文题名：Effect of liver-soothing and mind-regulating acupuncture on resting-state electroencephalographic signals in rats with post-traumatic stress disorder

作者：Wei Yu-ting[1];Yan Xing-ke[1];Han Ya-di[1];Zhang Yan-feng[1]

第一作者：魏玉桃

通信作者：Yan, XK[1]

机构：[1]Gansu Univ Chinese Med, Lanzhou 730000, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Lanzhou 730000, Gansu, Peoples R China.|[10735]甘肃中医药大学;

年份：2018

卷号：16

期号：5

起止页码：289

外文期刊名：JOURNAL OF ACUPUNCTURE AND TUINA SCIENCE

收录：WOS:【ESCI(收录号:WOS:000448185600001)】；

基金：This work was supported by Regional Science Fund of National Natural Science Foundation of China (No. 81460744); Natural Science Foundation of Gansu Province, China (No. 1308RJZA150).

语种：英文

外文关键词：Acupuncture Therapy; Point; Baihui (GV 20); Point; Shenmen (HT 7); Point; Neiguan (PC 6); Point; Taichong (LR 3); Stress Disorders; Post-traumatic; Electroencephalography; Rats

摘要：ObjectiveTo observe the effect of liver-soothing and mind-regulating acupuncture method on the resting-state electroencephalography (EEG) in rats with post-traumatic stress disorder (PTSD), and to provide evidence for the effect mechanism study and clinical application of acupuncture intervention for PTSD.MethodsSixty Sprague-Dawley (SD) rats were randomly divided into a blank control group, a model group, a grasping group, a paroxetine group and an acupuncture group, with 12 rats in each group. Except for rats in the blank control group, rats in the other groups were subjected to preparing the PTSD models using incarceration plus electric shock' method. After interventions, changes in rat behavior of each group were observed; changes in resting-state EEG were collected and analyzed with multichannel EEG acquisition and analysis system, and image analysis and statistical processing were performed.ResultsCompared with the blank control group, the average escape latency in the model group was significantly longer (P<0.05), and the times of crossing the platform and the effective areas were all significantly reduced (P<0.01). Compared with the grasping group, the average escape latencies in the paroxetine group and acupuncture group were significantly shortened (P<0.05), and the times of crossing the platform and the effective areas were all significantly increased (P<0.05). There were no significant differences in the average escape latency, the times of crossing the platform and the effective areas between the acupuncture group and paroxetine group (all P>0.05). Compared with the blank control group, the -wave power spectrum value in the model group was significantly decreased, and the power spectrum values of -wave, -wave and -wave were significantly increased (all P<0.01); compared with the grasping group, -wave power spectrum values in the paroxetine group and acupuncture group were significantly increased (both P<0.01), and the power spectrum values of -wave, -wave and -wave were decreased significantly (all P<0.01). The power spectrum values of -wave, -wave, -wave and -wave of rats in the acupuncture group were not significantly different from those in the paroxetine group (all P>0.05).ConclusionLiver-soothing and mind-regulating acupuncture method can significantly improve the abnormal EEG activity in PTSD rats, which may be one mechanism of liver-soothing and mind-regulating acupuncture method in effectively affecting the brain function in PTSD rats.