文献类型：期刊文献

中文题名：茯苓化学成分、药理作用及质量控制研究进展

英文题名：Research Progress on Chemical Constituents,Pharmacological Effects and Quality Control of Poria cocos

作者：叶青[1];刘东升[2,3];王兰霞[1,2,3];刘竞[1];张迈娜[1];高嘉雯[1];朱旭江[2,3]

第一作者：叶青

机构：[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃省药品检验研究院,甘肃兰州730030;[3]国家药品监督管理局中药材及饮片质量控制重点实验室,甘肃兰州730030

第一机构：甘肃中医药大学

年份：2023

卷号：40

期号：2

起止页码：75

中文期刊名：中医药信息

外文期刊名：Information on Traditional Chinese Medicine

基金：国家药品监督管理局中药材及饮片质量控制重点实验室项目(2021GSMPA-KL09);甘肃省药品产业技术扶持项目(2019KF003)。

语种：中文

中文关键词：茯苓;化学成分;药理作用;质量控制

外文关键词：Poria cocos;Chemical constituent;Pharmacological action;Quality control

摘要：中药材茯苓是真菌茯苓[Poria cocos(Schw)Wolf]的干燥菌核,来源于多孔菌科,是药食两用类中药,其有效成分和药理作用较多,现已在临床应用广泛。现对茯苓的化学成分、药理作用以及质量控制研究进行综述。发现茯苓主要化学成分为三萜类、二萜类、甾醇类、多糖类以及其他类化合物,其中研究最多的是三萜和多糖类化合物。茯苓的药理作用体现在机体多个方面,主要集中于泌尿系统、消化系统、中枢神经、免疫系统等,具有利尿、抗炎、镇静催眠、抗衰老等多种药理作用。质量控制方面,大部分文献报道主要集中于茯苓的指纹图谱和含量测定研究。
Poria cocos is the dry sclerotia of Poria cocos(Schw)Wolf,which belongs to porous fungi.It has a dual-purpose both for medication and for diet.It has many effective components and pharmacological effects and has been widely used in clinic.This study reviewed the researches on chemical components,pharmacological effects and quality control of Poria cocos.It is found that the main chemical components of Poria cocos include triterpenoids,diterpenes,sterols,polysaccharides and other compounds.Triterpenoids and polysaccharides are the most studied chemical components of Poria cocos.The pharmacological effects of Poria cocos are reflected in many aspects of the body,mainly concentrated in urinary system,digestive system,central nervous system and immune system.It has a variety of pharmacological effects including diuresis,anti-inflammation,sedative hypnosis and anti-aging.In terms of quality control,most of the literature reports mainly focused on the fingerprint and the content determination of Poria cocos.