详细信息
甘肃金银花对小鼠红细胞免疫功能影响的实验研究 被引量:9
Experimental Study of Gansu Honeysuckle on Immunologic Function of Erythrocytes in Mice
文献类型:期刊文献
中文题名:甘肃金银花对小鼠红细胞免疫功能影响的实验研究
英文题名:Experimental Study of Gansu Honeysuckle on Immunologic Function of Erythrocytes in Mice
作者:明海霞[1];陈彦文[1];王强[1];董晓丽[1];金戈[1];李扬[1];黄世佐[1]
第一作者:明海霞
机构:[1]甘肃中医学院,甘肃兰州730000
第一机构:甘肃中医药大学
年份:2012
卷号:25
期号:12
起止页码:16
中文期刊名:西部中医药
外文期刊名:Western Journal of Traditional Chinese Medicine
收录:CSTPCD
基金:甘肃中医学院中青年基金项目(编号05ZQ-04)
语种:中文
中文关键词:甘肃金银花;正品金银花;流式细胞术;红细胞免疫
外文关键词:Gans u honeysuckle; native honeysuckle; flow cytometry; immunologic function of erythrocyte
摘要:目的:比较甘肃金银花与正品金银花对小鼠红细胞免疫功能的影响。方法:采用流式细胞技术对小鼠红细胞的免疫黏附功能(C3bR受体和免疫复合物)进行测定,观察甘肃金银花与正品金银花对小鼠红细胞免疫功能影响的差异。结果:甘肃金银花和正品金银花干预的小鼠红细胞C3bR指数与病理性循环免疫复合物(IC)指数显著高于空白对照组(P<0.05),但甘肃金银花和正品金银花各浓度组之间无显著性差异。结论:甘肃金银花和正品金银花均可增加小鼠红细胞的免疫功能,即在红细胞免疫功能方面甘肃金银花与正品金银花具有相同的药用价值。
Objective: To compare the effects of Gansu honeysuckle and native one on immunologic function of red blood cells in mice. Method: Immunological and adhesive functions (C3bR receptor and immune complex) of erythrocytes in mice were detected by flow cytometry, the differences of Gansu honeysuckle and native one on immunologic function of erythrocytes in mice were observed and explored. Result: C3bR index and immune complex (IC)oferythrocytesinmiceof Gansu honeysuckle and native one groups were higher than that of blank group (P〈0.05)and there was no significant difference in different concentrations between groups of Gansu honeysuckle and native one. Conclusion:Gansu honeysuckle and native one can enhance immunologic function of erythrocytes in mice, i.e.Gansu honeysuckle and native one have the same medicinal values on immunologic function of erythrocytes.
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