文献类型：期刊文献

英文题名：Early childhood trauma and its long-term impact on cognitive and emotional development: a systematic review and meta-analysis

作者：Fan, Linlin[1];Kang, Tinghu[2]

第一作者：范琳琳

通信作者：Kang, TH[1]

机构：[1]Northwest Normal Univ, Gansu Univ Tradit Chinese Med, Dept Sch Nursing, Dept Sch Educ Sci, Lanzhou, Peoples R China;[2]Northwest Normal Univ, Dept Sch Psychol, Lanzhou, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Ruide Ave, Lanzhou 730030, Gansu, Peoples R China.

年份：2025

卷号：57

期号：1

外文期刊名：ANNALS OF MEDICINE

收录：;Scopus(收录号：2-s2.0-105011937683);WOS:【SCI-EXPANDED(收录号:WOS:001539221500001)】；

语种：英文

外文关键词：Cognitive development; emotional regulation; systematic review; meta-analysis; neurodevelopment; working memory; attention; childhood trauma

摘要：BackgroundChildhood trauma has profound, long-term effects on cognitive and emotional development. This systematic review and meta-analysis sought to synthesis the evidence around the long-term impact of human childhood trauma on domains of cognition and emotion in order to inform interventions and public health strategies.MethodsWe systematically reviewed 465 studies from PubMed, Cochrane Library, and Google Scholar, 9 studies were included after duplicates were removed and inclusion and exclusion criteria were applied, and all 9 studies were aimed at low-income people in the United States. Data on study design, trauma types, and cognitive/emotional outcomes were extracted. Study quality was assessed using the Newcastle-Ottawa Scale (NOS) and Cochrane Risk of Bias Tool (RoB 2). Random-effects meta-analysis and subgroup analyses (processing speed, attention, working memory, emotion regulation, executive function) were conducted using R software.ResultsChildhood trauma was associated with significant deficits in: Attention (SMD = 2.37, 95% CI: [5.75, 10.50]) Working memory (SMD = 3.55, 95% CI: [2.18, 9.28]) Emotion regulation (SMD = 1.25, 95% CI: [1.12, 3.62]) Executive function (SMD = 1.61, 95% CI: [0.06, 3.28]) Processing speed showed smaller deficits (SMD = -0.48, 95% CI: [-1.91, 0.94]). High heterogeneity (I2: 77-98%) reflected variability in trauma types and assessments. The pooled effect size (SMD = 1.57, 95% CI: [-0.12, 3.26]) highlighted trauma's pervasive impact.ConclusionChildhood trauma disproportionately impairs attention and working memory. These findings, however, point to the importance of early screening, trauma-informed care and targeted interventions to ameliorate the long-term consequences of trauma, even with high heterogeneity. Methodological variability should be addressed to inform prevention and treatment strategies in future research, as well as resilience factors explored.