文献类型：期刊文献

中文题名：基于“肺虚络瘀”理论探讨升陷汤治疗特发性肺纤维化

英文题名：Based on the Theory of "Lung Deficiency and Collateral Blood Stasis" to Explore the Treatment of Idiopathic Pulmonary Fibrosis with Shengxian Decoction

作者：李红梅[1];张旭辉[2];李世霞[1];漆哲宁[1]

第一作者：李红梅

机构：[1]甘肃中医药大学,甘肃兰州730000;[2]甘肃中医药大学附属医院,甘肃兰州730030

第一机构：甘肃中医药大学

年份：2022

卷号：34

期号：7

起止页码：1191

中文期刊名：中医药临床杂志

外文期刊名：Clinical Journal of Traditional Chinese Medicine

基金：兰州市城关区科技计划项目(项目编号:2021SHFZ0026)。

语种：中文

中文关键词：特发性肺纤维化(IPF);肺虚络瘀;升陷汤

外文关键词：Idiopathic pulmonary fibrosis(IPF);Lung deficiency and collaterals blood stasis;Shengxian decoction

摘要：特发性肺纤维化(IPF)是一种原因不明、以弥漫性肺泡炎和肺泡结构紊乱最终导致肺间质纤维化为特征的疾病,中医认为其病理性质为本虚标实,以肺、脾、肾三脏气虚下陷为本,痰浊、瘀血痹阻脉络为标,“肺虚络瘀”是其基本病机,治疗应以益气升陷、活血化瘀为原则,升陷汤源自《医学衷中参西录》,有补中益气、升阳举陷之效,擅于治疗气陷络瘀型肺痿。这为IPF患者提供了新的较为安全有效的治疗方式,亦为IPF的临床治疗提供新的用药指导。
Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology characterized by diffuse alveolitis and alveolar structural disorder eventually leading to pulmonary interstitial fibrosis.Traditional Chinese medicine believes that its pathological nature is based on deficiency and excess,and it is characterized by pulmonary fibrosis.spleen and kidney Qi deficiency is based on depression,phlegm turbidity,blood stasis and obstruction of collaterals are the signs,“lung deficiency and collateral stasis” is its basic pathogenesis,treatment should be based on the principles of nourishing Qi,promoting blood circulation and removing blood stasis.The soup is derived from “Zhongzhong Shenxilu Medicine”,which has the effect of invigorating the middle and benefiting the Qi,raising the yang and lifting the depression.This provides a new,safer and more effective treatment for IPF patients,as well as new medication guidance for the clinical treatment of IPF.