文献类型：期刊文献

英文题名：Telangiectatic osteosarcoma of the thoracic vertebra: a case report and literature review

作者：Wang, Chen[1];Fan, Xirong[1];Zhang, Kai[1];Xue, Wen[2];Li, Guoquan[3];Wang, Qilong[1];Gou, Fadong[1];Zhou, Yi[1];Xing, Wenbo[1];Wang, Chenjian[1]

第一作者：Wang, Chen

通信作者：Xue, W[1];Li, GQ[2]

机构：[1]Gansu Univ Chinese Med, Clin Med Coll 1, Lanzhou, Gansu, Peoples R China;[2]Gansu Prov Hosp, Lanzhou, Gansu, Peoples R China;[3]Qingshui Cty Peoples Hosp, Tianshui, Gansu, Peoples R China

第一机构：甘肃中医药大学

通信机构：[1]corresponding author), Gansu Prov Hosp, Lanzhou, Gansu, Peoples R China;[2]corresponding author), Qingshui Cty Peoples Hosp, Tianshui, Gansu, Peoples R China.

年份：2025

卷号：15

外文期刊名：FRONTIERS IN ONCOLOGY

收录：;Scopus(收录号：2-s2.0-105004199705);WOS:【SCI-EXPANDED(收录号:WOS:001479200300001)】；

基金：The author(s) declare that financial support was received for the research and/or publication of this article. This study was supported by Natural Science Foundation of Gansu Province (No. 23JRRA1280) and Gansu Provincial People's Hospital National Research Project Cultivation Program General Project (No. 19SYPYB-29).

语种：英文

外文关键词：telangiectatic osteosarcoma; thoracic vertebrae; case report; literature review; bone tumors

摘要：Telangiectatic osteosarcoma (TOS) is a rare high-grade malignant tumour found primarily in the metaphysis of long bones, but can also occur in the pelvis, spine and skull. Characterized by extensive vascular dilatation and aggressive behavior, TOS often has a poor prognosis and may be misdiagnosed due to similarities with other lesions. This report presents a case of TOS of the thoracic vertebrae and reviews the relevant literature to enhance clinical awareness. A 44-year-old woman presented with chest and back pain of worsening over two months, accompanied by lower limb numbness and incomplete paralysis. Initial treatment for "low back pain" proved ineffective. Imaging showed osteolytic destruction at T10, which led to surgery, and the tumour was classified as Tomita type III. The tumour was surgically resected, showing vascular proliferation and malignant stromal cells, confirming the pathological diagnosis of TOS. However, she developed complications requiring further surgery for recurrent problems, where a hematoma was discovered. Despite interventions, the patient's condition deteriorated, leading to the diagnosis of pulmonary metastasis and eventual death three months after the second surgery. This case highlights the need for increased awareness and accurate diagnosis of TOS, particularly in atypical presentations.