文献类型：期刊文献

英文题名：Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients

作者：Lin, Qing-Ling[1];Du, Hong-Liang[2];Xiong, Huai-Yu[3];Li, Bin[1];Liu, Jian[1];Xing, Xiao-Hua[4]

第一作者：Lin, Qing-Ling

通信作者：Xing, XH[1]

机构：[1]Lanzhou Univ, Hosp 1, Dept Intens Care Unit, Lanzhou, Gansu, Peoples R China;[2]Lanzhou Univ, Hosp 1, Dept Oral & Maxillofacial Surg, Lanzhou, Gansu, Peoples R China;[3]Lanzhou Univ, Lanzhou, Gansu, Peoples R China;[4]Gansu Univ Chinese Med, Affiliated Hosp, Dept Dent, 732 West Jiayuguan Rd, Lanzhou 730000, Gansu, Peoples R China

第一机构：Lanzhou Univ, Hosp 1, Dept Intens Care Unit, Lanzhou, Gansu, Peoples R China

通信机构：[1]corresponding author), Gansu Univ Chinese Med, Affiliated Hosp, Dept Dent, 732 West Jiayuguan Rd, Lanzhou 730000, Gansu, Peoples R China.|[10735b845793de6ae2b30]甘肃中医药大学第二附属医院;[10735]甘肃中医药大学;

年份：2020

卷号：15

期号：4

起止页码：445

外文期刊名：JOURNAL OF DENTAL SCIENCES

收录：;Scopus(收录号：2-s2.0-85077687830);WOS:【SCI-EXPANDED(收录号:WOS:000612608300008)】；

基金：This work was supported by the Natural Science Foundation of Gansu Province (grant number 1308RJZA240), Program of Lanzhou Science and Technology Development Plan (grant number 2018-3-57), Hospital Fund of the First Hospital of Lanzhou University (grant number ldyyyn2014-07), and the Science and Technology Projects of Gansu Province (grant number 18JR3RA344). We thank Kelly Zammit, BVSc, from Liwen Bianji, Edanz Group China (www.liwenbianji.cn/ac), for editing the English text of a draft of this manuscript.

语种：英文

外文关键词：Ludwig's angina; Intensive care unit; Length of hospital stay; Mortality

摘要：Background/Purpose: Ludwig's angina (LA) still presents regularly and various characteristics are documented, but patients admitted to the Intensive Care Unit (ICU) has not been studied. The purpose of this study was to investigate the clinical characteristics and outcomes of patients with LA who were admitted to ICU. Materials and methods: We retrospectively reviewed all 29 patients with LA who were admitted to the ICU of a university hospital from January 2013 to October 2018. Results were evaluated via descriptive analysis. The Log-Rank test was used to analyze the hospital/ICU length of stay (LOS). Results: The male: female ratio was 2.63:1. Mean age was 53.41 +/- 16.57 years (range 8-78 years). Concomitant conditions comprised diabetes mellitus in 10 patients (34.48%), and hypertension in six (20.69%). The main reason for ICU admission was surgical (44.83%). The mean Acute Physiology, Age, Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scores were 13.52 +/- 3.18 and 3.83 +/- 2.89, respectively. Twenty-eight patients (96.55%) received respiratory support. Sixteen patients (55.17%) had positive bacterial culture results. Fourteen bacterial strains were detected, most of which were gram-positive (72.72%). Mean LOS was 6.89 +/- 14.39 days (range 0.5-73 days), and 24.79 +/- 16 days in the hospital. The ICU mortality rate was 10.34%. Compared with LA patients without descending necrotizing mediastinitis (DNM), those with DNM had longer ICU and hospital LOS. The laboratory investigations were higher. Conclusion: LA patients in ICU were predominantly male, with a wide range age, high incidence of complications, long hospital LOS. (C) 2020 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.