文献类型：期刊文献

中文题名：针灸治疗慢性前列腺炎随机对照临床研究文献的Meta分析

英文题名：Meta Analysis of Randomized Controlled Clinical trials of Acupuncture Treatment for Chronic Prostatitis

作者：严兴科[1];崔海福[2];陈程[2];何天有[1]

第一作者：严兴科

机构：[1]甘肃中医学院,甘肃兰州730000;[2]长春中医药大学研究生学院,吉林长春130117

第一机构：甘肃中医药大学

年份：2012

卷号：23

期号：10

起止页码：2592

中文期刊名：时珍国医国药

外文期刊名：Lishizhen Medicine and Materia Medica Research

收录：北大核心:【北大核心2011】；CSCD:【CSCD_E2011_2012】；

基金：国家自然科学基金地区基金项目资助(No.2010-81060304)

语种：中文

中文关键词：针灸;慢性前列腺炎;临床随机对照试验;Meta分析

外文关键词：Acupuncture and moxibustion ; Chronic prostatitis ; RCT ; Meta - analysis

摘要：目的评价针灸治疗慢性前列腺炎的有效性,并对文献进行质量评价,分析临床研究的现状。方法检索2000～2011年8月VIP、CNKI、PubMed数据库关于针灸治疗慢性前列腺炎与常规药物比较的随机对照试验(RCT)和临床对照试验(CCT),采用RevMan4.2统计软件进行分析。结果 27篇文献符合纳入标准,共2828例患者。经Meta分析结果显示,针灸治疗慢性前列腺炎与药物对照组总有效率相比,有极其显著性差异[OR=3.66,其95%可信区间为(2.90,4.61),经Z检验,Z=10.99,P<0.00001]。针灸治疗与常规药物治疗慢性前列腺炎症状积分比较,统计学有极其显著性差异[WMD=-3.96,其95%可信区间为(-4.79,-3.13),经Z检验,Z=9.37,P<0.00001]。结论针灸对慢性前列腺炎疗效明显优于药物治疗,症状改善程度也明显优于药物治疗。但由于纳入的RCT、CCT研究文献少,随机、盲法、随访等方面应用的欠缺,且文献发表存在偏倚性,导致文献评价结果不能得出完全肯定的结论,其疗效及质量评价需要更多临床研究进行证实。
Objective To assess the efficacy of the acupuncture and moxibustion treatment on chronic prostatitis and to evaluate the quality of the literature. Methods Retrieveing the 2000 - 2011 VIP, CNKI, PubMed database ; collecting the clinical RCT on the acupuncture treatment of chronic prostatitis;selecting to meet the requirements of the randomized controlled trials （RCT） , con- trolled clinical trials （CCT） ;doing Meta- analysis of the literature according to the principles of evidence- based medicine. Re- sults A total of 27 the clinical RCT and 2828 cases of patients in this study. Meta analysis showed that the efficacy of the acu- puncture and moxibustion treatment on chronic prostatitis had significan difference as compared to the control group, [ OR = 1.21, 95 % CI （2.90,4.61）, Z = 10.99,P 〈 0. 00001 ] ;After acupuncture treatment of chronic prostatitis, the symptom score of the two groups had significant difference in comparison, [ WMD = -3.96,95% CI（ -4.79, -3.13 ）, Z = 9.37, P 〈 0. 00001 ]. Conclu- sion The therapeutic effect of acupuncture and moxibustion for chronic prostatitis is more obvious than control group in the aspects of total effectiveness and symptom scores. But because the quantity of documents in the aspects of RCT and CCT is not enough, es- pecially, it is less on high quality, large sample and multicenter randomized clinical study reports. And some of the publications have faults which exist bias, lack of random, blinding, adverse reactions and follow - up reports, which result in the incomplete clinical evaluation. Therefore, it is need to do more further study.