文献类型：期刊文献

中文题名：正交设计法优选加减身痛逐瘀汤提取工艺

英文题名：Optimization of Extraction Technology for Modified Shentong Zhuyu Decoction by Orthogonal Design

作者：刘凤霞[1];贺莉萍[2];张尚智[2];张环[2]

第一作者：刘凤霞

机构：[1]甘肃中医药大学定西校区药学部,定西743000;[2]甘肃中医药大学定西校区,定西743000

第一机构：甘肃中医药大学定西校区

年份：2023

卷号：32

期号：1

起止页码：91

中文期刊名：中央民族大学学报（自然科学版）

外文期刊名：Journal of Minzu University of China(Natural Sciences Edition)

基金：甘肃省定西市科技计划项目(DX2020Z04-2)。

语种：中文

中文关键词：加减身痛逐瘀汤;正交设计法;多指标综合评分法;提取工艺

外文关键词：modified Shentong Zhuyu Decoction;orthogonal test;multi-index comprehensive scoring;extraction technology

摘要：本文旨在优选加减身痛逐瘀汤的提取工艺。以龙胆苦苷、羌活醇、异欧前胡素的含量及干膏得率为考察指标,以溶剂倍数、提取温度、提取时间、提取次数为考察因素,采用L_(9)(3^(4))正交试验法,筛选加减身痛逐瘀汤的最佳提取工艺。结果表明,最佳提取工艺为加16倍量95%乙醇,于50℃超声提取3次,每次50min。优化后的提取工艺稳定可靠,为进一步开发利用该处方提供数据支持。
To optimize extraction conditions of modified Shentong Zhuyu Decoction.With the content of gentiopicrin,notopterygol and isoimperatorin and dry extract rate as indexes,L_(9)(3^(4))orthogonal design was used to screen the optimal extraction technology of modified Shentong Zhuyu Decoction with ethanol volume,extraction temperature,extraction time and extraction times as factors.Optimized extraction technology was extracted 3 times at 50℃with 16 times the amount of 95%ethanol,50min per time.This optimized extraction technology was stable and feasible,which can provide data support for the further development and utilization of the prescription.