文献类型：期刊文献

中文题名：针刺干预弱视的神经生物学机制研究进展

英文题名：Research advances in neurobiological mechanism of acupuncture for amblyopia

作者：马重兵[1];朱田田[1];刘安国[1];曹朝霞[1];严兴科[1]

第一作者：Ma Chong-bing

机构：[1]School of Acupuncture and Tuina, Gansu University of Chinese Medicine, Lanzhou 730000, China

第一机构：甘肃中医药大学针灸推拿学院

年份：2019

卷号：17

期号：4

起止页码：278

中文期刊名：Journal of Acupuncture and Tuina Science

外文期刊名：针灸推拿医学（英文版）

收录：CSTPCD;;Scopus;CSCD:【CSCD2019_2020】；

基金：国家自然科学基金,No.81860879,No.81660816,No.81260560;甘肃中医药大学中青年创新基金,No.ZQ2015-1.

语种：中文

中文关键词：针刺疗法;儿童;弱视;视觉;神经生物学;综述

外文关键词：Acupuncture Therapy;Child;Amblyopia;Vision, Ocular;Neurobiology;Review

摘要：弱视严重影响患儿生理及心理发育.针刺疗法是治疗弱视的有效方法之一,但对其机制尚未完全明确.从视皮层神经元形态学、视觉电生理、分子生物学等方面总结针刺干预弱视的机制,发现针刺通过修复视皮层神经元形态及超微结构损害,促进视觉通路及视皮层神经元电活动,调控视觉系统相关分子合成和表达水平达到干预弱视的目的.对于针刺干预弱视机制仍需进一步研究.
Amblyopia greatly affects the physical and mental development of children. Acupuncture is effective for amblyopia, though its mechanism remains unclear. This article summarized the mechanism of acupuncture treatment of amblyopia from the perspectives of morphology of neuro ns in visual cortex, visual electrophysiology, and molecular biology, etc. It was found that acup un cture may treat amblyopia through repairi ng the morphological and ultrastructural damages of n euro ns in visual cortex, promoting the electrical activities in visual pathway and visual cortical neurons, and modulating the synthesis and expression levels of factors involved in visual system. Nevertheless, further studies are required to unveil the mechanism of acupuncture treatment of amblyopia.