文献类型：期刊文献

中文题名：Adenosine triphosphate induced cell death: Mechanisms and implications in cancer biology and therapy

作者：Hao-Ling Zhang[1];Doblin Sandai[1];Zhong-Wen Zhang[2];Zhi-Jing Song[3];Dinesh Babu[4];Yasser Tabana[4];Sabbar Saad Dahham[5];Mowaffaq Adam Ahmed Adam[6];Yong Wang[7];Wei Wang[8];Hao-Long Zhang[1];Rui Zhao[3];Khaled Barakat[4];Mohammad Syamsul Reza Harun[1];Siti Nurfatimah Mohd Shapudin[1];Bronwyn Lok[1]

第一作者：Hao-Ling Zhang

机构：[1]Department of Biomedical Science,Advanced Medical and Dental Institute,University Sains Malaysia,Penang 13200,Malaysia;[2]School of Public Health,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu Province,China;[3]Clinical College of Chinese Medicine,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu Province,China;[4]Faculty of Pharmacy and Pharmaceutical Sciences,University of Alberta,Edmonton AB T6G 2E1,Canada;[5]Department of Science,University of Technology and Applied Sciences Rustaq,Rustaq 10 P.C.329,Oman;[6]Department of Chemistry and Biochemistry,San Diego State University,San Diego,CA 92182,United States;[7]Pathology Center,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu Province,China;[8]College of Acupuncture-Moxibustion and Tuina,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu Province,China

第一机构：Department of Biomedical Science,Advanced Medical and Dental Institute,University Sains Malaysia,Penang 13200,Malaysia

年份：2023

卷号：14

期号：12

起止页码：549

中文期刊名：World Journal of Clinical Oncology

外文期刊名：世界临床肿瘤学杂志（英文版）

收录：PubMed

基金：Supported by National Natural Science Foundation of China,No.81960877;University Innovation Fund of Gansu Province,No.2021A-076;Gansu Province Science and Technology Plan(Innovation Base and Talent Plan),No.21JR7RA561;Natural Science Foundation of Gansu Province,No.21JR1RA267 and No.22JR5RA582;Education Technology Innovation Project of Gansu Province,No.2022A-067;Innovation Fund of Higher Education of Gansu Province,No.2023A-088;Gansu Province Science and Technology Plan International Cooperation Field Project,No.23YFWA0005.

语种：英文

中文关键词：Adenosine triphosphate induced cell death;Adenosine triphosphate homeostasis;Mechanism;Cancer signaling pathways;Prognosis and clinical values;Cancer treatment

摘要：Adenosine triphosphate(ATP)induced cell death(AICD)is a critical cellular process that has garnered substantial scientific interest for its profound relevance to cancer biology and to therapeutic interventions.This comprehensive review unveils the intricate web of AICD mechanisms and their intricate connections with cancer biology.This review offers a comprehensive framework for comprehending the multifaceted role of AICD in the context of cancer.This is achieved by elucidating the dynamic interplay between systemic and cellular ATP homeostasis,deciphering the intricate mechanisms governing AICD,elucidating its intricate involvement in cancer signaling pathways,and scrutinizing validated key genes.Moreover,the exploration of AICD as a potential avenue for cancer treatment underscores its essential role in shaping the future landscape of cancer therapeutics.